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Research Article

Intron Definition and a Branch Site Adenosine at nt 385 Control RNA Splicing of HPV16 E6*I and E7 Expression

  • Masahiko Ajiro,

    Affiliation: Tumor Virus RNA Biology Section, HIV and AIDS Malignancy Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland, United States of America

    X
  • Rong Jia,

    Affiliation: Tumor Virus RNA Biology Section, HIV and AIDS Malignancy Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland, United States of America

    Current address: Wuhan University School of Stomatology and Key Laboratory for Oral Biomedicine of Ministry of Education, Hubei, China

    X
  • Lifang Zhang,

    Affiliation: Tumor Virus RNA Biology Section, HIV and AIDS Malignancy Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland, United States of America

    Current address: Wenzhou Medical College, Zhejiang, China

    X
  • Xuefeng Liu,

    Affiliation: Tumor Virus RNA Biology Section, HIV and AIDS Malignancy Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland, United States of America

    Current address: Georgetown University Medical School, Washington, D.C., United States of America

    X
  • Zhi-Ming Zheng mail

    zhengt@exchange.nih.gov

    Affiliation: Tumor Virus RNA Biology Section, HIV and AIDS Malignancy Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland, United States of America

    X
  • Published: October 04, 2012
  • DOI: 10.1371/journal.pone.0046412

About the Authors

Masahiko Ajiro, Rong Jia, Lifang Zhang, Xuefeng Liu, Zhi-Ming Zheng
Tumor Virus RNA Biology Section, HIV and AIDS Malignancy Branch, Center for Cancer Research, NCI, NIH, Bethesda, Maryland, United States of America

Corresponding Author

Email: zhengt@exchange.nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ZMZ MA RJ. Performed the experiments: MA RJ LZ XL. Analyzed the data: MA RJ LZ XL ZMZ. Wrote the paper: MA RJ ZMZ.