About the Authors

Fumihiko Takeuchi

Affiliation Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan

Masato Isono

Affiliation Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan

Tomohiro Katsuya

Affiliations Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita, Japan, Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Japan

Mitsuhiro Yokota

Affiliation Department of Genome Science, Aichi-Gakuin University, School of Dentistry, Nagoya, Japan

Ken Yamamoto

Affiliation Department of Molecular Genetics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

Toru Nabika

Affiliation Department of Functional Pathology, Shimane University School of Medicine, Izumo, Japan

Kazuro Shimokawa

Affiliation Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan

Eitaro Nakashima

Affiliations Division of Endocrinology and Diabetes, Department of Internal Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan, Department of Diabetes and Endocrinology, Chubu Rosai Hospital, Nagoya, Japan

Takao Sugiyama

Affiliation Institute for Adult Diseases, Asahi Life Foundation, Tokyo, Japan

Hiromi Rakugi

Affiliation Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Japan

Shuhei Yamaguchi

Affiliation Department of Internal Medicine III, Shimane University School of Medicine, Izumo, Japan

Toshio Ogihara

Affiliations Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Japan, Morinomiya University of Medical Sciences, Osaka, Japan

Yukio Yamori

Affiliation Mukogawa Women's University Institute for World Health Development, Nishinomiya, Japan

Norihiro Kato

nokato@ri.ncgm.go.jp

Affiliation Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NK TO YY. Performed the experiments: MI KY. Analyzed the data: FT KS. Contributed reagents/materials/analysis tools: TK MY TN EN TS HR SY. Wrote the paper: NK FT.