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Research Article

Tolerogenic Dendritic Cells That Inhibit Autoimmune Arthritis Can Be Induced by a Combination of Carvacrol and Thermal Stress

  • Rachel Spiering,

    Affiliation: Department of Infectious Diseases and Immunology, Utrecht University, Utrecht, The Netherlands

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  • Ruurd van der Zee,

    Affiliation: Department of Infectious Diseases and Immunology, Utrecht University, Utrecht, The Netherlands

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  • Josée Wagenaar,

    Affiliation: Department of Infectious Diseases and Immunology, Utrecht University, Utrecht, The Netherlands

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  • Dimos Kapetis,

    Affiliation: Department of Biotechnology and Bioscience, Genopolis, University of Milano-Bicocca, Milan, Italy

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  • Francesca Zolezzi,

    Affiliation: Department of Biotechnology and Bioscience, Genopolis, University of Milano-Bicocca, Milan, Italy

    Current address: Singapore Immunology Network (SIgN), Singapore, Singapore

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  • Willem van Eden,

    Affiliation: Department of Infectious Diseases and Immunology, Utrecht University, Utrecht, The Netherlands

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  • Femke Broere mail

    f.broere@uu.nl

    Affiliation: Department of Infectious Diseases and Immunology, Utrecht University, Utrecht, The Netherlands

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  • Published: September 25, 2012
  • DOI: 10.1371/journal.pone.0046336

About the Authors

Rachel Spiering, Ruurd van der Zee, Josée Wagenaar, Willem van Eden, Femke Broere
Department of Infectious Diseases and Immunology, Utrecht University, Utrecht, The Netherlands
Dimos Kapetis, Francesca Zolezzi
Department of Biotechnology and Bioscience, Genopolis, University of Milano-Bicocca, Milan, Italy

Corresponding Author

Email: f.broere@uu.nl

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RS FZ FB. Performed the experiments: RS JW DK. Analyzed the data: RS DK. Wrote the paper: RS RvdZ WvE FB.