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Research Article

Hepatoprotective Effect of MMP-19 Deficiency in a Mouse Model of Chronic Liver Fibrosis

  • Marketa Jirouskova equal contributor,

    equal contributor Contributed equally to this work with: Marketa Jirouskova, Olga Zbodakova

    Affiliation: Institute of Molecular Genetics of the ASCR, Prague, Czech Republic

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  • Olga Zbodakova equal contributor,

    equal contributor Contributed equally to this work with: Marketa Jirouskova, Olga Zbodakova

    Affiliation: Institute of Molecular Genetics of the ASCR, Prague, Czech Republic

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  • Martin Gregor,

    Affiliation: Institute of Molecular Genetics of the ASCR, Prague, Czech Republic

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  • Karel Chalupsky,

    Affiliation: Institute of Molecular Genetics of the ASCR, Prague, Czech Republic

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  • Lenka Sarnova,

    Affiliation: Institute of Molecular Genetics of the ASCR, Prague, Czech Republic

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  • Marian Hajduch,

    Affiliation: Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital in Olomouc, Olomouc, Czech Republic

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  • Jiri Ehrmann,

    Affiliations: Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital in Olomouc, Olomouc, Czech Republic, Department of Clinical and Molecular Pathology, Faculty of Medicine and Dentistry, Palacky University and University Hospital in Olomouc, Olomouc, Czech Republic

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  • Marie Jirkovska,

    Affiliation: Institute of Histology and Embryology, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic

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  • Radislav Sedlacek mail

    radislav.sedlacek@img.cas.cz

    Affiliation: Institute of Molecular Genetics of the ASCR, Prague, Czech Republic

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  • Published: October 09, 2012
  • DOI: 10.1371/journal.pone.0046271

About the Authors

Marketa Jirouskova, Olga Zbodakova, Martin Gregor, Karel Chalupsky, Lenka Sarnova, Radislav Sedlacek
Institute of Molecular Genetics of the ASCR, Prague, Czech Republic
Marian Hajduch, Jiri Ehrmann
Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital in Olomouc, Olomouc, Czech Republic
Jiri Ehrmann
Department of Clinical and Molecular Pathology, Faculty of Medicine and Dentistry, Palacky University and University Hospital in Olomouc, Olomouc, Czech Republic
Marie Jirkovska
Institute of Histology and Embryology, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic

Corresponding Author

Email: radislav.sedlacek@img.cas.cz

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: M. Jirouskova OZ MG KC LS RS. Performed the experiments: M. Jirouskova OZ MG KC LS. Analyzed the data: M. Jirouskova OZ MG KC LS MH JE M. Jirkovska. Wrote the paper: M. Jirouskova OZ MG KC RS.