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Research Article

Combining Epidemiological and Genetic Networks Signifies the Importance of Early Treatment in HIV-1 Transmission

  • Narges Zarrabi mail,

    N.Zarrabi@uva.nl

    Affiliation: Computational Science, University of Amsterdam, Amsterdam, The Netherlands

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  • Mattia Prosperi,

    Affiliations: College of Medicine, Department of Pathology, Immunology and Laboratory Medicine, Emerging Pathogens Institute, University of Florida, Gainesville, Florida, United States of America, Clinic of Infectious Diseases, Catholic University of Sacred Heart, Rome, Italy

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  • Robert G. Belleman,

    Affiliation: Computational Science, University of Amsterdam, Amsterdam, The Netherlands

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  • Manuela Colafigli,

    Affiliation: Clinic of Infectious Diseases, Catholic University of Sacred Heart, Rome, Italy

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  • Andrea De Luca,

    Affiliations: Clinic of Infectious Diseases, Catholic University of Sacred Heart, Rome, Italy, Unit of Infectious Diseases, Siena University Hospital, Siena, Italy

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  • Peter M. A. Sloot

    Affiliations: Computational Science, University of Amsterdam, Amsterdam, The Netherlands, National Research University ITMO, St. Petersburg, Russia, Nanyang Technological University, Singapore, Singapore

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  • Published: September 28, 2012
  • DOI: 10.1371/journal.pone.0046156

About the Authors

Narges Zarrabi, Robert G. Belleman, Peter M. A. Sloot
Computational Science, University of Amsterdam, Amsterdam, The Netherlands
Mattia Prosperi
College of Medicine, Department of Pathology, Immunology and Laboratory Medicine, Emerging Pathogens Institute, University of Florida, Gainesville, Florida, United States of America
Mattia Prosperi, Manuela Colafigli, Andrea De Luca
Clinic of Infectious Diseases, Catholic University of Sacred Heart, Rome, Italy
Andrea De Luca
Unit of Infectious Diseases, Siena University Hospital, Siena, Italy
Peter M. A. Sloot
National Research University ITMO, St. Petersburg, Russia
Peter M. A. Sloot
Nanyang Technological University, Singapore, Singapore

Corresponding Author

Email: N.Zarrabi@uva.nl

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Performed the phylogenetic analysis: MP. Provided the visualization support: RGB. Conceived and designed the experiments: NZ PMAS. Performed the experiments: NZ. Analyzed the data: MP MC ADL NZ RGB PMAS. Contributed reagents/materials/analysis tools: NZ MP RGB. Wrote the paper: NZ MP RGB MC ADL PMAS.