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Research Article

Overexpression of HTRA1 Leads to Down-Regulation of Fibronectin and Functional Changes in RF/6A Cells and HUVECs

  • Jingjing Jiang equal contributor,

    equal contributor Contributed equally to this work with: Jingjing Jiang, Lvzhen Huang

    Affiliations: Department of Ophthalmology, Peking University People's Hospital, Beijing, China, Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China, Department of Ophthalmology, China-Japan Friendship Hospital, Beijing, China

    X
  • Lvzhen Huang equal contributor,

    equal contributor Contributed equally to this work with: Jingjing Jiang, Lvzhen Huang

    Affiliations: Department of Ophthalmology, Peking University People's Hospital, Beijing, China, Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China

    X
  • Wenzhen Yu,

    Affiliations: Department of Ophthalmology, Peking University People's Hospital, Beijing, China, Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China

    X
  • Xi Wu,

    Affiliations: Department of Ophthalmology, Peking University People's Hospital, Beijing, China, Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China

    X
  • Peng Zhou,

    Affiliations: Department of Ophthalmology, Peking University People's Hospital, Beijing, China, Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China, Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China

    X
  • Xiaoxin Li mail

    drlixiaoxin@163.com

    Affiliations: Department of Ophthalmology, Peking University People's Hospital, Beijing, China, Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China

    X
  • Published: October 08, 2012
  • DOI: 10.1371/journal.pone.0046115

About the Authors

Jingjing Jiang, Lvzhen Huang, Wenzhen Yu, Xi Wu, Peng Zhou, Xiaoxin Li
Department of Ophthalmology, Peking University People's Hospital, Beijing, China
Jingjing Jiang, Lvzhen Huang, Wenzhen Yu, Xi Wu, Peng Zhou, Xiaoxin Li
Key Laboratory of Vision Loss and Restoration, Ministry of Education, Beijing, China
Jingjing Jiang
Department of Ophthalmology, China-Japan Friendship Hospital, Beijing, China
Peng Zhou
Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China

Corresponding Author

Email: drlixiaoxin@163.com

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: XL JJ LH WY PZ. Performed the experiments: LH JJ WY. Analyzed the data: JJ LH XL WY XW. Contributed reagents/materials/analysis tools: XL JJ LH. Wrote the paper: JJ LH.