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Research Article

Effects of Aerobic Exercise Training on Cardiac Renin-Angiotensin System in an Obese Zucker Rat Strain

  • Diego Lopes Mendes Barretti,

    Affiliations: Laboratory of Biochemistry and Molecular Biology of Exercise, School of Physical Education and Sport, University of São Paulo, São Paulo, Brazil, Experimental Physiopathology, University of São Paulo, Medical School, São Paulo, Brazil

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  • Flávio de Castro Magalhães,

    Affiliation: Laboratory of Biochemistry and Molecular Biology of Exercise, School of Physical Education and Sport, University of São Paulo, São Paulo, Brazil

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  • Tiago Fernandes,

    Affiliation: Laboratory of Biochemistry and Molecular Biology of Exercise, School of Physical Education and Sport, University of São Paulo, São Paulo, Brazil

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  • Everton Crivoi do Carmo,

    Affiliation: Laboratory of Biochemistry and Molecular Biology of Exercise, School of Physical Education and Sport, University of São Paulo, São Paulo, Brazil

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  • Kaleizu Teodoro Rosa,

    Affiliation: Heart Institute (InCor), University of São Paulo, Medical School, São Paulo, Brazil

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  • Maria Claudia Irigoyen,

    Affiliation: Heart Institute (InCor), University of São Paulo, Medical School, São Paulo, Brazil

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  • Carlos Eduardo Negrão,

    Affiliations: Laboratory of Biochemistry and Molecular Biology of Exercise, School of Physical Education and Sport, University of São Paulo, São Paulo, Brazil, Heart Institute (InCor), University of São Paulo, Medical School, São Paulo, Brazil

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  • Edilamar Menezes Oliveira mail

    edilamar@usp.br

    Affiliations: Laboratory of Biochemistry and Molecular Biology of Exercise, School of Physical Education and Sport, University of São Paulo, São Paulo, Brazil, Experimental Physiopathology, University of São Paulo, Medical School, São Paulo, Brazil

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  • Published: October 12, 2012
  • DOI: 10.1371/journal.pone.0046114

About the Authors

Diego Lopes Mendes Barretti, Flávio de Castro Magalhães, Tiago Fernandes, Everton Crivoi do Carmo, Carlos Eduardo Negrão, Edilamar Menezes Oliveira
Laboratory of Biochemistry and Molecular Biology of Exercise, School of Physical Education and Sport, University of São Paulo, São Paulo, Brazil
Diego Lopes Mendes Barretti, Edilamar Menezes Oliveira
Experimental Physiopathology, University of São Paulo, Medical School, São Paulo, Brazil
Kaleizu Teodoro Rosa, Maria Claudia Irigoyen, Carlos Eduardo Negrão
Heart Institute (InCor), University of São Paulo, Medical School, São Paulo, Brazil

Corresponding Author

Email: edilamar@usp.br

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EMO CEN. Performed the experiments: DLMB FCM TF ECDC. Analyzed the data: DLMB EMO. Contributed reagents/materials/analysis tools: MCI KTR. Wrote the paper: DLMB EMO FCM.