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Research Article

Acute Erythemal Ultraviolet Radiation Causes Systemic Immunosuppression in the Absence of Increased 25-Hydroxyvitamin D3 Levels in Male Mice

  • Shelley Gorman mail,

    shelleyg@ichr.uwa.edu.au

    Affiliation: Telethon Institute for Child Health Research and Centre for Child Health Research, University of Western Australia, Perth, Western Australia, Australia

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  • Naomi M. Scott,

    Affiliation: Telethon Institute for Child Health Research and Centre for Child Health Research, University of Western Australia, Perth, Western Australia, Australia

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  • Daryl H. W. Tan,

    Affiliation: Telethon Institute for Child Health Research and Centre for Child Health Research, University of Western Australia, Perth, Western Australia, Australia

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  • Clare E. Weeden,

    Affiliation: Telethon Institute for Child Health Research and Centre for Child Health Research, University of Western Australia, Perth, Western Australia, Australia

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  • Robert C. Tuckey,

    Affiliation: School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia. Perth, Western Australia, Australia

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  • Jacqueline L. Bisley,

    Affiliation: Telethon Institute for Child Health Research and Centre for Child Health Research, University of Western Australia, Perth, Western Australia, Australia

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  • Michele A. Grimbaldeston,

    Affiliation: Division of Human Immunology, Centre for Cancer Biology, SA Pathology, Adelaide, South Australia, Australia

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  • Prue H. Hart

    Affiliation: Telethon Institute for Child Health Research and Centre for Child Health Research, University of Western Australia, Perth, Western Australia, Australia

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  • Published: September 26, 2012
  • DOI: 10.1371/journal.pone.0046006

About the Authors

Shelley Gorman, Naomi M. Scott, Daryl H. W. Tan, Clare E. Weeden, Jacqueline L. Bisley, Prue H. Hart
Telethon Institute for Child Health Research and Centre for Child Health Research, University of Western Australia, Perth, Western Australia, Australia
Robert C. Tuckey
School of Biomedical, Biomolecular and Chemical Sciences, University of Western Australia. Perth, Western Australia, Australia
Michele A. Grimbaldeston
Division of Human Immunology, Centre for Cancer Biology, SA Pathology, Adelaide, South Australia, Australia

Corresponding Author

Email: shelleyg@ichr.uwa.edu.au

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SG DHWT MAG PHH. Performed the experiments: SG NMS DHWT CEW RCT JLB PHH. Analyzed the data: SG NMS DHWT CEW RCT MAG PHH. Wrote the paper: SG PHH.