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Research Article

Omega-3 Polyunsaturated Fatty Acids Antagonize Macrophage Inflammation via Activation of AMPK/SIRT1 Pathway

  • Bingzhong Xue mail,

    bxue@gsu.edu (BX); hshi3@gsu.edu (HS)

    Affiliations: Department of Biology, Georgia State University, Atlanta, Georgia, United States of America, Department of Internal Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina, United States of America

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  • Zhenggang Yang,

    Affiliation: Department of Internal Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina, United States of America

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  • Xianfeng Wang,

    Affiliation: Department of Internal Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina, United States of America

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  • Hang Shi mail

    bxue@gsu.edu (BX); hshi3@gsu.edu (HS)

    Affiliations: Department of Biology, Georgia State University, Atlanta, Georgia, United States of America, Department of Internal Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina, United States of America

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  • Published: October 05, 2012
  • DOI: 10.1371/journal.pone.0045990

About the Authors

Bingzhong Xue, Hang Shi
Department of Biology, Georgia State University, Atlanta, Georgia, United States of America
Bingzhong Xue, Zhenggang Yang, Xianfeng Wang, Hang Shi
Department of Internal Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BX HS. Performed the experiments: BX HS ZY XW. Analyzed the data: BX HS. Wrote the paper: BX HS.