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Research Article

The Geographical Distribution of Leadership in Globalized Clinical Trials

  • Jarno Hoekman mail,

    j.hoekman@umcg.nl

    Affiliation: Department of Clinical Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

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  • Koen Frenken,

    Affiliation: School of Innovation Sciences, Eindhoven University of Technology, Eindhoven, The Netherlands

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  • Dick de Zeeuw,

    Affiliation: Department of Clinical Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

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  • Hiddo Lambers Heerspink

    Affiliation: Department of Clinical Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

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  • Published: October 10, 2012
  • DOI: 10.1371/journal.pone.0045984

About the Authors

Jarno Hoekman, Dick de Zeeuw, Hiddo Lambers Heerspink
Department of Clinical Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
Koen Frenken
School of Innovation Sciences, Eindhoven University of Technology, Eindhoven, The Netherlands

Corresponding Author

Email: j.hoekman@umcg.nl

Competing Interests

DZ has been a steering committee member in trials sponsored by Abbott (Radar, Vital), AstraZeneca (Planets), Novartis (Altitude), Reata Pharmaceuticals (Beacon), Amgen (Treat), Johnson & Johnson (Canvas), Keryx (SUN) and MSD (Sharp). His institution has received honoraria for his work. HLH has been a steering committee member in trials sponsored by Abbott (Radar) and Reata Pharmaceuticals (Beacon). His institution has received honoraria for his work. There are no other relationships or activities that could appear to have influenced the submitted work. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JH KF HLH DZ. Performed the experiments: JH HLH. Analyzed the data: JH HLH. Wrote the paper: JH KF HLH DZ. Wrote the first draft: JH.