About the Authors

Matthieu Bouaziz

matthieu.x.bouaziz@gmail.com

Affiliations Department of Biostatistics, Pharnext, Paris, France, Statistics and Genome Laboratory, University of Evry Val d'Essonne, UMR CNRS 8071 - USC INRA, Evry, France

Caroline Paccard

Affiliation Department of Biostatistics, Pharnext, Paris, France

Mickael Guedj

Affiliation Department of Biostatistics, Pharnext, Paris, France

Christophe Ambroise

Affiliation Statistics and Genome Laboratory, University of Evry Val d'Essonne, UMR CNRS 8071 - USC INRA, Evry, France

Competing Interests

MB, CP and MG are employees of Pharnext, Paris. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MB MG CA. Performed the experiments: MB CP. Analyzed the data: MB CP. Contributed reagents/materials/analysis tools: MB CP. Wrote the paper: MB. Conceived and designed the method: MB MG CA.