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Research Article

Dysregulation of MicroRNAs in Colonic Field Carcinogenesis: Implications for Screening

  • Dhananjay P. Kunte,

    Affiliation: Department of Medicine, NorthShore University HealthSystem, Evanston, Illinois, United States of America

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  • Mart DelaCruz,

    Affiliation: Department of Medicine, NorthShore University HealthSystem, Evanston, Illinois, United States of America

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  • Ramesh K. Wali,

    Affiliation: Department of Medicine, NorthShore University HealthSystem, Evanston, Illinois, United States of America

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  • Ashwaty Menon,

    Affiliation: Department of Medicine, NorthShore University HealthSystem, Evanston, Illinois, United States of America

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  • Hongyan Du,

    Affiliation: Department of Medicine, NorthShore University HealthSystem, Evanston, Illinois, United States of America

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  • Yolanda Stypula,

    Affiliation: Department of Biomedical Engineering, Northwestern University, Evanston, Illinois, United States of America

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  • Amir Patel,

    Affiliation: Department of Medicine, NorthShore University HealthSystem, Evanston, Illinois, United States of America

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  • Vadim Backman,

    Affiliation: Department of Biomedical Engineering, Northwestern University, Evanston, Illinois, United States of America

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  • Hemant K. Roy mail

    h-roy@northwestern.edu

    Affiliation: Department of Medicine, NorthShore University HealthSystem, Evanston, Illinois, United States of America

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  • Published: September 25, 2012
  • DOI: 10.1371/journal.pone.0045591

About the Authors

Dhananjay P. Kunte, Mart DelaCruz, Ramesh K. Wali, Ashwaty Menon, Hongyan Du, Amir Patel, Hemant K. Roy
Department of Medicine, NorthShore University HealthSystem, Evanston, Illinois, United States of America
Yolanda Stypula, Vadim Backman
Department of Biomedical Engineering, Northwestern University, Evanston, Illinois, United States of America

Corresponding Author

Email: h-roy@northwestern.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DPK HKR. Performed the experiments: DPK RKW MD AM AP YS. Analyzed the data: DPK HD VB HKR. Wrote the paper: HKR DPK.