About the Authors

Simone Buraschi

Contributed equally to this work with: Simone Buraschi, Thomas Neill

Affiliation Department of Pathology, Anatomy and Cell Biology, and the Cancer Cell Biology and Signaling Program, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

Thomas Neill

Contributed equally to this work with: Simone Buraschi, Thomas Neill

Affiliation Department of Pathology, Anatomy and Cell Biology, and the Cancer Cell Biology and Signaling Program, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

Rick T. Owens

Affiliation LifeCell Corporation, Branchburg, New Jersey, United States of America

Leonardo A. Iniguez

Affiliation Roche NimbleGen, Inc., Research and Development, Madison, Wisconsin, United States of America

George Purkins

Affiliation Department of Pathology, Anatomy and Cell Biology, and the Cancer Cell Biology and Signaling Program, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

Rajanikanth Vadigepalli

Affiliation Department of Pathology, Anatomy and Cell Biology, and the Cancer Cell Biology and Signaling Program, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

Barry Evans

Affiliation Department of Pathology, Anatomy and Cell Biology, and the Cancer Cell Biology and Signaling Program, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

Liliana Schaefer

Affiliation Department of Pharmacology, Goethe University, Frankfurt, Germany

Stephen C. Peiper

Affiliation Department of Pathology, Anatomy and Cell Biology, and the Cancer Cell Biology and Signaling Program, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

Zi-Xuan Wang

Affiliation Department of Pathology, Anatomy and Cell Biology, and the Cancer Cell Biology and Signaling Program, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

Renato V. Iozzo

iozzo@kimmelcancercenter.org

Affiliation Department of Pathology, Anatomy and Cell Biology, and the Cancer Cell Biology and Signaling Program, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America

Competing Interests

RTO works for LifeCell Co. and has provided the recombinant decorin used for the studies. LAI works for Roche-NibleGen Co. and has provided expertise in performing the microarray data. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: RVI SB TN. Performed the experiments: SB TN. Analyzed the data: RVI SB TN GP RV BE LS Z-XW. Contributed reagents/materials/analysis tools: RTO LAI SCP Z-XW. Wrote the paper: RVI SB TN.