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Research Article

Notch Signalling Inhibits CD4 Expression during Initiation and Differentiation of Human T Cell Lineage

  • Stephen M. Carlin,

    Affiliation: Blood Stem Cells and Cancer Research, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia

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  • Melissa L. M. Khoo,

    Affiliation: Blood Stem Cells and Cancer Research, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia

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  • David D. Ma,

    Affiliations: Blood Stem Cells and Cancer Research, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia, Haematology Department, St Vincent's Hospital, Sydney, New South Wales, Australia

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  • John J. Moore mail

    jmoore@stvincents.com.au

    Affiliation: Haematology Department, St Vincent's Hospital, Sydney, New South Wales, Australia

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  • Published: October 12, 2012
  • DOI: 10.1371/journal.pone.0045342

About the Authors

Stephen M. Carlin, Melissa L. M. Khoo, David D. Ma
Blood Stem Cells and Cancer Research, St Vincent's Centre for Applied Medical Research, Sydney, New South Wales, Australia
David D. Ma, John J. Moore
Haematology Department, St Vincent's Hospital, Sydney, New South Wales, Australia

Corresponding Author

Email: jmoore@stvincents.com.au

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SMC MLK JJM. Performed the experiments: SMC MLK. Analyzed the data: SMC MLK. Wrote the paper: SMC MLK DDM JJM.