About the Authors

Fan Wang

Affiliations Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, United States of America, Veterans Affairs (VA) Medical Center, VA Connecticut Healthcare System, West Haven, Connecticut, United States of America

Joel Gelernter

Affiliations Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, United States of America, Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America, Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut, United States of America, Veterans Affairs (VA) Medical Center, VA Connecticut Healthcare System, West Haven, Connecticut, United States of America

Henry R. Kranzler

Affiliation Department of Psychiatry, University of Pennsylvania Perelman School of Medicine and VISN4 Mental Illness Research, Education and Clinical Center (MIRECC), Philadelphia Veterans Affairs Medical Center (VAMC), Philadelphia, Pennsylvania, United States of America

Huiping Zhang

huiping.zhang@yale.edu

Affiliations Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, United States of America, Veterans Affairs (VA) Medical Center, VA Connecticut Healthcare System, West Haven, Connecticut, United States of America

Competing Interests

The authors have read the journal's policy and have the following conflicts: Dr. Kranzler has received compensation for professional services from the National Institutes of Health (National Institute on Alcohol Abuse and Alcoholism) (NIAAA) and National Institute on Drug Abuse (NIDA)) and for academic lectures and editorial functions in various scientific venues (including the ACNP). Dr. Kranzler has had consulting arrangements with the following pharmaceutical companies: Alkermes, Lilly, Lundbeck, Pfizer and Roche. Dr. Kranzler also receives support from the Alcohol Clinical Trials Initiative (ACTIVE), which Eli Lilly, Schering Plough, Lundbeck, Alkermes, GlaxoSmithKline, Abbott, and Johnson & Johnson support. Dr. Gelernter has received compensation for professional services in the previous three years from the following entities: Yale University School of Medicine, Veterans Affairs Healthcare System (VA), and the National Institutes of Health (NIAAA, NIDA, and NIMH), and related to academic lectures and editorial functions in various scientific venues (including the ACNP). Other authors have no conflict of interest to report. The competing interest does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HZ HRK JG. Performed the experiments: FW HZ. Analyzed the data: FW HZ. Contributed reagents/materials/analysis tools: JG HRK. Wrote the paper: FW HZ JG HRK.