Advertisement
Research Article

Compensatory Feto-Placental Upregulation of the Nitric Oxide System during Fetal Growth Restriction

  • Silvia Pisaneschi,

    Affiliations: Division of Obstetrics and Gynecology, Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, Italy, Institute of Life Sciences, Scuola Superiore Sant’Anna, Pisa, Italy

    X
  • Francesca A. L. Strigini,

    Affiliation: Division of Obstetrics and Gynecology, Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, Italy

    X
  • Angel M. Sanchez,

    Affiliation: Division of Obstetrics and Gynecology, Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, Italy

    X
  • Silvia Begliuomini,

    Affiliation: Division of Obstetrics and Gynecology, Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, Italy

    X
  • Elena Casarosa,

    Affiliation: Division of Obstetrics and Gynecology, Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, Italy

    X
  • Andrea Ripoli,

    Affiliation: Institute of Clinical Physiology, National Research Council, Pisa, Italy

    X
  • Paolo Ghirri,

    Affiliation: Division of Neonatology, Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, Italy

    X
  • Antonio Boldrini,

    Affiliation: Division of Neonatology, Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, Italy

    X
  • Bruno Fink,

    Affiliation: Noxygen Science Transfer and Diagnostics, Elzach, Germany

    X
  • Andrea R. Genazzani,

    Affiliation: Division of Obstetrics and Gynecology, Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, Italy

    X
  • Flavio Coceani,

    Affiliation: Institute of Life Sciences, Scuola Superiore Sant’Anna, Pisa, Italy

    X
  • Tommaso Simoncini mail

    tommaso.simoncini@med.unipi.it

    Affiliation: Division of Obstetrics and Gynecology, Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, Italy

    X
  • Published: September 27, 2012
  • DOI: 10.1371/journal.pone.0045294

About the Authors

Silvia Pisaneschi, Francesca A. L. Strigini, Angel M. Sanchez, Silvia Begliuomini, Elena Casarosa, Andrea R. Genazzani, Tommaso Simoncini
Division of Obstetrics and Gynecology, Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, Italy
Paolo Ghirri, Antonio Boldrini
Division of Neonatology, Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, Italy
Andrea Ripoli
Institute of Clinical Physiology, National Research Council, Pisa, Italy
Bruno Fink
Noxygen Science Transfer and Diagnostics, Elzach, Germany
Silvia Pisaneschi, Flavio Coceani
Institute of Life Sciences, Scuola Superiore Sant’Anna, Pisa, Italy

Corresponding Author

Email: tommaso.simoncini@med.unipi.it

Competing Interests

B. Fink is the Business Manager of Noxygen Science Transfer & Diagnostics, a company that provides a service to measure NO-Hb in biological fluids and other samples. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials. None of the other authors have conflicts of interest.

Author Contributions

Conceived and designed the experiments: SP TS. Performed the experiments: SP AMS EC BF SB FALS PG AB. Analyzed the data: SP AR ARG FC TS. Wrote the paper: SP FC TS.