Advertisement
Research Article

The Zebrafish Homologue of the Human DYT1 Dystonia Gene Is Widely Expressed in CNS Neurons but Non-Essential for Early Motor System Development

  • Jonathan J. Sager,

    Affiliations: Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Pittsburgh Institute of Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

    X
  • Gonzalo E. Torres,

    Affiliations: Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Department of Pharmacology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Pittsburgh Institute of Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

    X
  • Edward A. Burton mail

    eab25@pitt.edu

    Affiliations: Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Pittsburgh Institute of Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Geriatric Research, Education and Clinical Center, Pittsburgh Veterans Affairs Healthcare System, Pittsburgh, Pennsylvania, United States of America, Department of Neurology, Pittsburgh Veterans Affairs Healthcare System, Pittsburgh, Pennsylvania, United States of America

    X
  • Published: September 28, 2012
  • DOI: 10.1371/journal.pone.0045175

About the Authors

Jonathan J. Sager, Gonzalo E. Torres
Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
Jonathan J. Sager, Edward A. Burton
Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
Gonzalo E. Torres
Department of Pharmacology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
Edward A. Burton
Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
Jonathan J. Sager, Gonzalo E. Torres, Edward A. Burton
Pittsburgh Institute of Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
Edward A. Burton
Geriatric Research, Education and Clinical Center, Pittsburgh Veterans Affairs Healthcare System, Pittsburgh, Pennsylvania, United States of America
Edward A. Burton
Department of Neurology, Pittsburgh Veterans Affairs Healthcare System, Pittsburgh, Pennsylvania, United States of America

Corresponding Author

Email: eab25@pitt.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JJS GET EAB. Performed the experiments: JJS EAB. Analyzed the data: JJS EAB. Contributed reagents/materials/analysis tools: GET EAB. Wrote the paper: JJS GET EAB.