Model Hirano Bodies Protect against Tau-Independent and Tau-Dependent Cell Death Initiated by the Amyloid Precursor Protein Intracellular Domain

Matthew Furgerson; Marcus Fechheimer; Ruth Furukawa

doi:10.1371/journal.pone.0044996

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Open Access

Peer-reviewed

Research Article

Model Hirano Bodies Protect against Tau-Independent and Tau-Dependent Cell Death Initiated by the Amyloid Precursor Protein Intracellular Domain

Matthew Furgerson,

Affiliation Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, United States of America
⨯
Marcus Fechheimer,

Affiliation Department of Cellular Biology, University of Georgia, Athens, Georgia, United States of America
⨯
Ruth Furukawa

* E-mail: furukawa@uga.edu

Affiliation Department of Cellular Biology, University of Georgia, Athens, Georgia, United States of America
⨯

Model Hirano Bodies Protect against Tau-Independent and Tau-Dependent Cell Death Initiated by the Amyloid Precursor Protein Intracellular Domain

Matthew Furgerson,
Marcus Fechheimer,
Ruth Furukawa

Published: September 18, 2012
https://doi.org/10.1371/journal.pone.0044996

About the Authors

Matthew Furgerson

Affiliation Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, United States of America

Marcus Fechheimer

Affiliation Department of Cellular Biology, University of Georgia, Athens, Georgia, United States of America

Ruth Furukawa

* E-mail: furukawa@uga.edu

Affiliation Department of Cellular Biology, University of Georgia, Athens, Georgia, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: M. Furgerson M. Fechheimer RF. Performed the experiments: M. Furgerson. Analyzed the data: M. Furgerson RF M. Fechheimer. Contributed reagents/materials/analysis tools: M. Furgerson RF M. Fechheimer. Wrote the paper: M. Furgerson RF.

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Cell death
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Alzheimer's disease
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Neurodegenerative diseases
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