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Research Article

Sepsis-Induced Acute Lung Injury (ALI) Is Milder in Diabetic Rats and Correlates with Impaired NFkB Activation

  • Luciano R. Filgueiras, Jr.,

    Affiliation: Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

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  • Joilson O. Martins,

    Affiliation: Department of Clinical and Toxicological Analyses, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil

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  • Carlos H. Serezani,

    Affiliation: Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

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  • Vera L. Capelozzi,

    Affiliation: Department of Pathology, Faculty of Medicine, University of São Paulo, São Paulo, Brazil

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  • Marlise B. A. Montes,

    Affiliation: Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

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  • Sonia Jancar mail

    sojancar@icb.usp.br

    Affiliation: Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

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  • Published: September 14, 2012
  • DOI: 10.1371/journal.pone.0044987

About the Authors

Luciano R. Filgueiras, Jr., Marlise B. A. Montes, Sonia Jancar
Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil
Joilson O. Martins
Department of Clinical and Toxicological Analyses, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil
Carlos H. Serezani
Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
Vera L. Capelozzi
Department of Pathology, Faculty of Medicine, University of São Paulo, São Paulo, Brazil

Corresponding Author

Email: sojancar@icb.usp.br

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LFR JOM CHS SJ. Performed the experiments: LFR MBAM. Analyzed the data: LFR JOM CHS VLC SJ. Contributed reagents/materials/analysis tools: CHS SJ. Wrote the paper: LFR CHS SJ.