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Research Article

Type III Interferons, IL-28 and IL-29, Are Increased in Chronic HCV Infection and Induce Myeloid Dendritic Cell-Mediated FoxP3+ Regulatory T Cells

  • Angela Dolganiuc,

    Affiliation: Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Karen Kodys,

    Affiliation: Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Christopher Marshall,

    Affiliation: Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Banishree Saha,

    Affiliation: Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Shuye Zhang,

    Affiliation: Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Shashi Bala,

    Affiliation: Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Gyongyi Szabo mail

    Gyongyi.Szabo@umassmed.edu

    Affiliation: Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Published: October 10, 2012
  • DOI: 10.1371/journal.pone.0044915

About the Authors

Angela Dolganiuc, Karen Kodys, Christopher Marshall, Banishree Saha, Shuye Zhang, Shashi Bala, Gyongyi Szabo
Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Corresponding Author

Email: Gyongyi.Szabo@umassmed.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AD GS. Performed the experiments: AD KK BS SZ. Analyzed the data: AD GS SB. Wrote the paper: AD GS. Contributed to patient selection, recruitment and clinical correlations: CM.