About the Authors
- Yifan Xing
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Affiliations Shandong University Qilu Hospital Research Center for Cell Therapy, Key Laboratory of Cardiovascular Remodeling and Function Research, Jinan, China, Department of Traditional Medicine, Qilu Hospital of Shandong University, Jinan, China, Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America
- Ting Niu
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Affiliation Shandong University Qilu Hospital Research Center for Cell Therapy, Key Laboratory of Cardiovascular Remodeling and Function Research, Jinan, China
- Wenjuan Wang
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Affiliations Shandong University Qilu Hospital Research Center for Cell Therapy, Key Laboratory of Cardiovascular Remodeling and Function Research, Jinan, China, Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America
- Jinqing Li
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Affiliation Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America
- Siying Li
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Affiliations Shandong University Qilu Hospital Research Center for Cell Therapy, Key Laboratory of Cardiovascular Remodeling and Function Research, Jinan, China, Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America
- Joseph S. Janicki
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Affiliation Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America
- Stacey Ruiz
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Affiliation Department of Pharmacology, Reata Pharmaceuticals, Inc., Irving, Texas, United States of America
- Colin J. Meyer
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Affiliation Department of Pharmacology, Reata Pharmaceuticals, Inc., Irving, Texas, United States of America
- Xing Li Wang
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Affiliation Shandong University Qilu Hospital Research Center for Cell Therapy, Key Laboratory of Cardiovascular Remodeling and Function Research, Jinan, China
- Dongqi Tang
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Affiliations Shandong University Qilu Hospital Research Center for Cell Therapy, Key Laboratory of Cardiovascular Remodeling and Function Research, Jinan, China, Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America
- Yuxia Zhao
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* E-mail: yuxia_zhao@126.com (YZ); taixing.cui@uscmed.sc.edu (TC)
Affiliation Department of Traditional Medicine, Qilu Hospital of Shandong University, Jinan, China
- Taixing Cui
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* E-mail: yuxia_zhao@126.com (YZ); taixing.cui@uscmed.sc.edu (TC)
Affiliations Shandong University Qilu Hospital Research Center for Cell Therapy, Key Laboratory of Cardiovascular Remodeling and Function Research, Jinan, China, Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America
Competing Interests
Stacey Ruiz and Colin J. Meyer are employed by Reata Pharmaceuticals, Inc. Reata Pharmaceuticals, Inc, synthesized, purified, and provided dihydro-CDDOtrifluoroethyl amide (dh404), which Reata Pharmaceuticals has a patent on. Reata Pharmaceuticals has numerous compounds in development from this same class of compounds. There are no marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.
Author Contributions
Conceived and designed the experiments: YX JL TC. Performed the experiments: YX TN WW JL SL. Analyzed the data: YX TN WW JL SL XLW DT TC. Contributed reagents/materials/analysis tools: SR CJM YZ TC. Wrote the paper: JSJ TC.