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Research Article

Quantifying the Clinical Significance of Cannabis Withdrawal

  • David J. Allsop mail,

    d.allsop@unsw.edu.au

    Affiliation: National Cannabis Prevention and Information Centre, National Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales, Australia

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  • Jan Copeland,

    Affiliation: National Cannabis Prevention and Information Centre, National Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales, Australia

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  • Melissa M. Norberg,

    Affiliation: National Cannabis Prevention and Information Centre, National Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales, Australia

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  • Shanlin Fu,

    Affiliation: Centre for Forensic Science, School of Chemistry and Forensic Science, University of Technology Sydney (UTS), New South Wales, Australia

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  • Anna Molnar,

    Affiliation: Centre for Forensic Science, School of Chemistry and Forensic Science, University of Technology Sydney (UTS), New South Wales, Australia

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  • John Lewis,

    Affiliation: Centre for Forensic Science, School of Chemistry and Forensic Science, University of Technology Sydney (UTS), New South Wales, Australia

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  • Alan J. Budney

    Affiliation: Geisel School of Medicine at Dartmouth, Hanover, Lebanon, New Hampshire, United States of America

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  • Published: September 26, 2012
  • DOI: 10.1371/journal.pone.0044864

About the Authors

David J. Allsop, Jan Copeland, Melissa M. Norberg
National Cannabis Prevention and Information Centre, National Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales, Australia
Shanlin Fu, Anna Molnar, John Lewis
Centre for Forensic Science, School of Chemistry and Forensic Science, University of Technology Sydney (UTS), New South Wales, Australia
Alan J. Budney
Geisel School of Medicine at Dartmouth, Hanover, Lebanon, New Hampshire, United States of America

Corresponding Author

Email: d.allsop@unsw.edu.au

Competing Interests

Professor Alan Budney has provided consultation to GW Pharmaceuticals. Dr. Allsop, Professor Copeland, and Dr. Norberg are currently carrying out an investigator driven clinical trial using materials donated by GW Pharmaceuticals. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials. All other authors report no competing interest exists.

Author Contributions

Conceived and designed the experiments: DJA JC MMN AJB. Performed the experiments: DJA. Analyzed the data: DJA. Contributed reagents/materials/analysis tools: SF AM JL. Wrote the paper: DJA JC MN AJB.