About the Authors

M. Jerry Wright Jr

Affiliation Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, California, United States of America

Deepshikha Angrish

Affiliation Department of Chemistry, The Scripps Research Institute, La Jolla, California, United States of America

Shawn M. Aarde

Affiliation Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, California, United States of America

Deborah J. Barlow

Affiliation Department of Pharmaceutical Sciences, University of New England, Portland, Maine, United States of America

Matthew W. Buczynski

Affiliation Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, California, United States of America

Kevin M. Creehan

Affiliation Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, California, United States of America

Sophia A. Vandewater

Affiliation Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, California, United States of America

Loren H. Parsons

Affiliation Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, California, United States of America

Karen L. Houseknecht

Affiliation Department of Pharmaceutical Sciences, University of New England, Portland, Maine, United States of America

Tobin J. Dickerson

Affiliation Department of Chemistry, The Scripps Research Institute, La Jolla, California, United States of America

Michael A. Taffe

mtaffe@scripps.edu

Affiliation Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, California, United States of America

Competing Interests

The co-author MAT is a PLoS ONE Editorial Board member. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MJW MAT SMA MWB LHP DA TJD KLH. Performed the experiments: DA DJB KMC SAV MWB. Analyzed the data: MAT KLH MJB MJW KMC. Contributed reagents/materials/analysis tools: DA TJD. Wrote the paper: MAT. Assisted MAT with refining the analysis and presentation of results: MJW SMA KLH MWB TJD. Assisted MAT with the logic of the study and interpretation of the data: MJW SMA KLH MWB TJD.