Hypoxic Induction of the Regulator of G-Protein Signalling 4 Gene Is Mediated by the Hypoxia-Inducible Factor Pathway

Sam W. Z. Olechnowicz; Anthony O. Fedele; Daniel J. Peet

doi:10.1371/journal.pone.0044564

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Open Access

Peer-reviewed

Research Article

Hypoxic Induction of the Regulator of G-Protein Signalling 4 Gene Is Mediated by the Hypoxia-Inducible Factor Pathway

Sam W. Z. Olechnowicz,

Current address: Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom

Affiliations School of Molecular and Biomedical Science, University of Adelaide, Adelaide, Australia, ARC Special Research Centre for the Molecular Genetics of Development, University of Adelaide, Adelaide, Australia
⨯
Anthony O. Fedele,

Affiliation Lysosomal Diseases Research Unit (LDRU), SA Pathology, North Adelaide, Australia
⨯
Daniel J. Peet

* E-mail: daniel.peet@adelaide.edu.au

Affiliations School of Molecular and Biomedical Science, University of Adelaide, Adelaide, Australia, ARC Special Research Centre for the Molecular Genetics of Development, University of Adelaide, Adelaide, Australia
⨯

Hypoxic Induction of the Regulator of G-Protein Signalling 4 Gene Is Mediated by the Hypoxia-Inducible Factor Pathway

Sam W. Z. Olechnowicz,
Anthony O. Fedele,
Daniel J. Peet

Published: September 7, 2012
https://doi.org/10.1371/journal.pone.0044564

About the Authors

Sam W. Z. Olechnowicz

Current address: Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom

Affiliations School of Molecular and Biomedical Science, University of Adelaide, Adelaide, Australia, ARC Special Research Centre for the Molecular Genetics of Development, University of Adelaide, Adelaide, Australia

Anthony O. Fedele

Affiliation Lysosomal Diseases Research Unit (LDRU), SA Pathology, North Adelaide, Australia

Daniel J. Peet

* E-mail: daniel.peet@adelaide.edu.au

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SWZO AF DJP. Performed the experiments: SWZO AF. Analyzed the data: SWZO AF DJP. Wrote the paper: SWZO AF DJP.

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Hypoxia
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Gene expression
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Small interfering RNA
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Transfection
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Mammalian genomics
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Human genomics
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Luciferase
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Medical hypoxia
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