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Research Article

Determinants of Recovery from Severe Posterior Reversible Encephalopathy Syndrome

  • Stephane Legriel mail,

    slegriel@ch-versailles.fr

    Affiliation: Medical-Surgical Intensive Care Department, CH Versailles – Site André Mignot, Le Chesnay, France

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  • Olivier Schraub,

    Affiliation: Medical-Surgical Intensive Care Department, CH Versailles – Site André Mignot, Le Chesnay, France

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  • Elie Azoulay,

    Affiliation: Medical Intensive Care Department, CHU Saint-Louis, Paris, France

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  • Philippe Hantson,

    Affiliation: Intensive Care Department, Cliniques Universitaires Saint-Luc, Brussels, Belgium

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  • Eric Magalhaes,

    Affiliation: Neurology Department and Stroke Center, CH Versailles - André Mignot, Le Chesnay, France

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  • Isaline Coquet,

    Affiliation: Medical-Surgical Intensive Care Department, Hopital Foch, Suresnes, France

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  • Cedric Bretonniere,

    Affiliation: Intensive Care Department, CHU de Nantes - Hôtel Dieu, Nantes, France

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  • Olivier Gilhodes,

    Affiliation: Medical-Surgical Intensive Care Department, CHI de Créteil, Créteil, France

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  • Nadia Anguel,

    Affiliation: Medical Intensive Care Department, Chu de Bicêtre, Kremlin-Bicêtre, France

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  • Bruno Megarbane,

    Affiliation: Medical Intensive Care Department, CHU Lariboisière, Paris, France

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  • Laurent Benayoun,

    Affiliation: Surgical Intensive Care Department, CHU Beaujon, Clichy, France

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  • David Schnell,

    Affiliation: Medical Intensive Care Department, CHU Saint-Louis, Paris, France

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  • Gaetan Plantefeve,

    Affiliation: Medical-Surgical Intensive Care Department, CH Victor Dupouy, Argenteuil, France

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  • Julien Charpentier,

    Affiliation: Medical Intensive Care Department, CHU Cochin, Paris, France

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  • Laurent Argaud,

    Affiliation: Medical Intensive Care, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France

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  • Bruno Mourvillier,

    Affiliation: Medical Intensive Care Department, CHU Bichat, Paris, France

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  • Arnaud Galbois,

    Affiliation: Medical Intensive Care Department, CHU Saint Antoine, Paris, France

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  • Ludivine Chalumeau-Lemoine,

    Affiliation: Medical Intensive Care Department, CHU Tenon, Paris, France

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  • Michel Rivoal,

    Affiliation: Medical-Surgical Intensive Care Department, CH Arpajon, Arpajon, France

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  • François Durand,

    Affiliation: Hepatology and Liver Intensive care, CHU Beaujon, Clichy, France

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  • Arnaud Geffroy,

    Affiliation: Surgical Intensive Care Department, CHU Bichat, Paris, France

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  • Marc Simon,

    Affiliation: Intensive Care Department, Cliniques du Sud-Luxembourg of Arlon, Arlon, Belgium

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  • Annabelle Stoclin,

    Affiliation: Medical-Surgical Intensive Care Department, Institut Gustave Roussy, Villejuif, France

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  • Jean-Louis Pallot,

    Affiliation: Medical-Surgical Intensive Care Department, CH André Grégoire, Montreuil, France

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  • Charlotte Arbelot,

    Affiliation: Surgical Intensive Care Department, CHU Pitié Salpétrière, Paris, France

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  • Martine Nyunga,

    Affiliation: Medical-Surgical Intensive Care Department, CH de Roubaix, Roubaix, France

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  • Olivier Lesieur,

    Affiliation: Medical-Surgical Intensive Care Department, CH de La Rochelle, La Rochelle, France

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  • Gilles Troché,

    Affiliation: Medical-Surgical Intensive Care Department, CH Versailles – Site André Mignot, Le Chesnay, France

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  • Fabrice Bruneel,

    Affiliation: Medical-Surgical Intensive Care Department, CH Versailles – Site André Mignot, Le Chesnay, France

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  • Yves-Sébastien Cordoliani,

    Affiliation: Radiology Department, Hôpital privé de Parly II, Le Chesnay, France

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  • Jean-Pierre Bedos,

    Affiliation: Medical-Surgical Intensive Care Department, CH Versailles – Site André Mignot, Le Chesnay, France

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  • Fernando Pico, on behalf of the Critically Ill Posterior Reversible Encephalopathy Syndrome Study group (CYPRESS)

    Affiliation: Neurology Department and Stroke Center, CH Versailles - André Mignot, Le Chesnay, France

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  • Published: September 14, 2012
  • DOI: 10.1371/journal.pone.0044534

About the Authors

Stephane Legriel, Olivier Schraub, Gilles Troché, Fabrice Bruneel, Jean-Pierre Bedos
Medical-Surgical Intensive Care Department, CH Versailles – Site André Mignot, Le Chesnay, France
Elie Azoulay, David Schnell
Medical Intensive Care Department, CHU Saint-Louis, Paris, France
Philippe Hantson
Intensive Care Department, Cliniques Universitaires Saint-Luc, Brussels, Belgium
Eric Magalhaes, Fernando Pico
Neurology Department and Stroke Center, CH Versailles - André Mignot, Le Chesnay, France
Isaline Coquet
Medical-Surgical Intensive Care Department, Hopital Foch, Suresnes, France
Cedric Bretonniere
Intensive Care Department, CHU de Nantes - Hôtel Dieu, Nantes, France
Olivier Gilhodes
Medical-Surgical Intensive Care Department, CHI de Créteil, Créteil, France
Nadia Anguel
Medical Intensive Care Department, Chu de Bicêtre, Kremlin-Bicêtre, France
Bruno Megarbane
Medical Intensive Care Department, CHU Lariboisière, Paris, France
Laurent Benayoun
Surgical Intensive Care Department, CHU Beaujon, Clichy, France
Gaetan Plantefeve
Medical-Surgical Intensive Care Department, CH Victor Dupouy, Argenteuil, France
Julien Charpentier
Medical Intensive Care Department, CHU Cochin, Paris, France
Laurent Argaud
Medical Intensive Care, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France
Bruno Mourvillier
Medical Intensive Care Department, CHU Bichat, Paris, France
Arnaud Galbois
Medical Intensive Care Department, CHU Saint Antoine, Paris, France
Ludivine Chalumeau-Lemoine
Medical Intensive Care Department, CHU Tenon, Paris, France
Michel Rivoal
Medical-Surgical Intensive Care Department, CH Arpajon, Arpajon, France
François Durand
Hepatology and Liver Intensive care, CHU Beaujon, Clichy, France
Arnaud Geffroy
Surgical Intensive Care Department, CHU Bichat, Paris, France
Marc Simon
Intensive Care Department, Cliniques du Sud-Luxembourg of Arlon, Arlon, Belgium
Annabelle Stoclin
Medical-Surgical Intensive Care Department, Institut Gustave Roussy, Villejuif, France
Jean-Louis Pallot
Medical-Surgical Intensive Care Department, CH André Grégoire, Montreuil, France
Charlotte Arbelot
Surgical Intensive Care Department, CHU Pitié Salpétrière, Paris, France
Martine Nyunga
Medical-Surgical Intensive Care Department, CH de Roubaix, Roubaix, France
Olivier Lesieur
Medical-Surgical Intensive Care Department, CH de La Rochelle, La Rochelle, France
Yves-Sébastien Cordoliani
Radiology Department, Hôpital privé de Parly II, Le Chesnay, France

Corresponding Author

Email: slegriel@ch-versailles.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SL FP. Performed the experiments: SL OS EA PH EM IC CB OG NA B. Megarbane LB DS GP JC LA B. Mourvillier A. Galbois LCL MR FD A. Geffroy MS AS JLP CA MN OL GT FB YSC JPB FP. Analyzed the data: SL EA OS. Wrote the paper: SL OS EA PH EM IC CB OG NA B. Megarbane LB DS GP JC LA B. Mourvillier A. Galbois LCL MR FD A. Geffroy MS AS JLP CA MN OL GT FB YSC JPB FP.