About the Authors

Jose C. Florez

dppmail@biostat.bsc.gwu.edu (DPPRG); jcflorez@partners.org (JCF)

Affiliations Center for Human Genetic Research and Diabetes Research Center (Diabetes Unit), Massachusetts General Hospital, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

Kathleen A. Jablonski

Affiliation The Biostatistics Center, George Washington University, Rockville, Maryland, United States of America

Jarred B. McAteer

Affiliations Center for Human Genetic Research and Diabetes Research Center (Diabetes Unit), Massachusetts General Hospital, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America

Paul W. Franks

Affiliations Lund University Diabetes Center, Department of Clinical Sciences, Lund University, Malmö, Sweden, Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America

Clinton C. Mason

Affiliation Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona, United States of America

Kieren Mather

Affiliation Division of Endocrinology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America

Edward Horton

Affiliations Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America, Joslin Diabetes Center, Boston, Massachusetts, United States of America

Ronald Goldberg

Affiliation Lipid Disorders Clinic, Division of Endocrinology, Diabetes, and Metabolism, and the Diabetes Research Institute, Leonard M. Miller School of Medicine, University of Miami, Miami, Florida, United States of America

Dana Dabelea

Affiliation Department of Preventive Medicine and Biometrics, University of Colorado at Denver and Health Sciences Center, Denver, Colorado, United States of America

Steven E. Kahn

Affiliation Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, VA Puget Sound Health Care System and University of Washington, Seattle, Washington, United States of America

Richard F. Arakaki

Affiliation Department of Medicine Clinical Research, University of Hawaii, Honolulu, Hawaii, United States of America

Alan R. Shuldiner

Affiliation Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

William C. Knowler

A list of Diabetes Prevention Program Research Group investigators is provided in the Appendix S1.

Affiliation Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona, United States of America

Competing Interests

JCF has received consulting honoraria from Novartis, Pfizer and Eli Lilly. Bristol-Myers Squibb and Parke-Davis provided medication. LifeScan Inc., Health O Meter, Hoechst Marion Roussel, Inc., Merck-Medco Managed Care, Inc., Merck and Co., Nike Sports Marketing, Slim Fast Foods Co., and Quaker Oats Co. donated materials, equipment, or medicines for concomitant conditions. McKesson BioServices Corp., Matthews Media Group, Inc., and the Henry M. Jackson Foundation provided support services under subcontract with the Coordinating Center. The authors also received funding from the commercial source Novo Nordisk. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: JCF KAJ PWF ARS WCK. Performed the experiments: JCF JBM. Analyzed the data: KAJ JCF CCM WCK. Contributed reagents/materials/analysis tools: KM EH RG SEK RFA WCK. Wrote the paper: JCF. Reviewed and edited the manuscript: KM EH RG SEK RFA WCK JCF KAJ PWF ARS JBM CCM DD.