Advertisement
Research Article

MiR-214 Targets β-Catenin Pathway to Suppress Invasion, Stem-Like Traits and Recurrence of Human Hepatocellular Carcinoma

  • Hongping Xia,

    Affiliation: Bek Chai Heah Laboratory of Cancer Genomics, Division of Cellular and Molecular Research, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore, Singapore

    X
  • London Lucien P. J. Ooi,

    Affiliation: Department of Surgical Oncology, Singapore General Hospital, Singapore, Singapore

    X
  • Kam M. Hui mail

    cmrhkm@nccs.com.sg

    Affiliations: Bek Chai Heah Laboratory of Cancer Genomics, Division of Cellular and Molecular Research, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore, Singapore, Cancer and Stem Cell Biology Program, Duke-NUS Graduate Medical School, Singapore, Singapore, Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Institute of Molecular and Cell Biology, A*STAR, Biopolis Drive Proteos, Singapore, Singapore

    X
  • Published: September 04, 2012
  • DOI: 10.1371/journal.pone.0044206

About the Authors

Hongping Xia, Kam M. Hui
Bek Chai Heah Laboratory of Cancer Genomics, Division of Cellular and Molecular Research, Humphrey Oei Institute of Cancer Research, National Cancer Centre, Singapore, Singapore
London Lucien P. J. Ooi
Department of Surgical Oncology, Singapore General Hospital, Singapore, Singapore
Kam M. Hui
Cancer and Stem Cell Biology Program, Duke-NUS Graduate Medical School, Singapore, Singapore
Kam M. Hui
Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
Kam M. Hui
Institute of Molecular and Cell Biology, A*STAR, Biopolis Drive Proteos, Singapore, Singapore

Corresponding Author

Email: cmrhkm@nccs.com.sg

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KMH. Performed the experiments: HPX. Analyzed the data: KMH HPX. Contributed reagents/materials/analysis tools: LLPJO HPX KMH. Wrote the paper: HPX KMH. NA.