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Research Article

Expression of TRPV1 Channels after Nerve Injury Provides an Essential Delivery Tool for Neuropathic Pain Attenuation

  • Hossain Md. Zakir equal contributor,

    equal contributor Contributed equally to this work with: Hossain Md. Zakir, Rahman Md. Mostafeezur

    Affiliation: Division of Oral Physiology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

    X
  • Rahman Md. Mostafeezur equal contributor,

    equal contributor Contributed equally to this work with: Hossain Md. Zakir, Rahman Md. Mostafeezur

    Affiliation: Division of Oral Physiology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

    X
  • Akiko Suzuki,

    Affiliation: Division of Oral Anatomy, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

    X
  • Suzuro Hitomi,

    Affiliation: Department of Physiology, Nihon University School of Dentistry, Tokyo, Japan

    X
  • Ikuko Suzuki,

    Affiliation: Department of Physiology, Nihon University School of Dentistry, Tokyo, Japan

    X
  • Takeyasu Maeda,

    Affiliation: Division of Oral Anatomy, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

    X
  • Kenji Seo,

    Affiliation: Division of Dental Anesthesiology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

    X
  • Yoshiaki Yamada,

    Affiliation: Division of Oral Physiology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

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  • Kensuke Yamamura,

    Affiliation: Division of Oral Physiology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

    X
  • Shaya Lev,

    Affiliation: Department of Medical Neurobiology, Institute for Medical Research Israel Canada and Center for Research on Pain, The Hebrew University Medical School, Jerusalem, Israel

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  • Alexander M. Binshtok,

    Affiliation: Department of Medical Neurobiology, Institute for Medical Research Israel Canada and Center for Research on Pain, The Hebrew University Medical School, Jerusalem, Israel

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  • Koichi Iwata,

    Affiliation: Department of Physiology, Nihon University School of Dentistry, Tokyo, Japan

    X
  • Junichi Kitagawa mail

    kitagawa@dent.niigata-u.ac.jp

    Affiliation: Division of Oral Physiology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

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  • Published: September 04, 2012
  • DOI: 10.1371/journal.pone.0044023

About the Authors

Hossain Md. Zakir, Rahman Md. Mostafeezur, Yoshiaki Yamada, Kensuke Yamamura, Junichi Kitagawa
Division of Oral Physiology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Akiko Suzuki, Takeyasu Maeda
Division of Oral Anatomy, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Suzuro Hitomi, Ikuko Suzuki, Koichi Iwata
Department of Physiology, Nihon University School of Dentistry, Tokyo, Japan
Kenji Seo
Division of Dental Anesthesiology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
Shaya Lev, Alexander M. Binshtok
Department of Medical Neurobiology, Institute for Medical Research Israel Canada and Center for Research on Pain, The Hebrew University Medical School, Jerusalem, Israel

Corresponding Author

Email: kitagawa@dent.niigata-u.ac.jp

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HMZ TM KS YY KY AMB KI JK. Performed the experiments: HMZ RMM AS SH IS JK. Analyzed the data: HMZ RMM AMB JK. Wrote the paper: HMZ SL AMB KI JK.