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Research Article

Blood Glutathione S-Transferase-π as a Time Indicator of Stroke Onset

  • Natacha Turck mail,

    natacha.turck@unige.ch

    Affiliation: Biomedical Proteomics Research Group, Department of Human Protein Sciences, Faculty of Medicine, Geneva, Switzerland

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  • Xavier Robin,

    Affiliations: Biomedical Proteomics Research Group, Department of Human Protein Sciences, Faculty of Medicine, Geneva, Switzerland, Swiss Institute of Bioinformatics, Medical University Centre, Geneva, Switzerland

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  • Nadia Walter,

    Affiliation: Biomedical Proteomics Research Group, Department of Human Protein Sciences, Faculty of Medicine, Geneva, Switzerland

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  • Catherine Fouda,

    Affiliation: Biomedical Proteomics Research Group, Department of Human Protein Sciences, Faculty of Medicine, Geneva, Switzerland

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  • Alexandre Hainard,

    Affiliation: Biomedical Proteomics Research Group, Department of Human Protein Sciences, Faculty of Medicine, Geneva, Switzerland

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  • Roman Sztajzel,

    Affiliation: Department of Neurology, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland

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  • Ghislaine Wagner,

    Affiliation: Department of Neurology, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland

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  • Denis F. Hochstrasser,

    Affiliation: Biomedical Proteomics Research Group, Department of Human Protein Sciences, Faculty of Medicine, Geneva, Switzerland

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  • Joan Montaner,

    Affiliation: Neurovascular Research Laboratory, VHIR & Stroke Unit, Vall d'Hebron Hospital, Autonomous University of Barcelona (UAB), Catalonia, Spain

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  • Pierre R. Burkhard,

    Affiliation: Department of Neurology, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland

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  • Jean-Charles Sanchez

    Affiliation: Biomedical Proteomics Research Group, Department of Human Protein Sciences, Faculty of Medicine, Geneva, Switzerland

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  • Published: September 17, 2012
  • DOI: 10.1371/journal.pone.0043830

About the Authors

Natacha Turck, Xavier Robin, Nadia Walter, Catherine Fouda, Alexandre Hainard, Denis F. Hochstrasser, Jean-Charles Sanchez
Biomedical Proteomics Research Group, Department of Human Protein Sciences, Faculty of Medicine, Geneva, Switzerland
Xavier Robin
Swiss Institute of Bioinformatics, Medical University Centre, Geneva, Switzerland
Roman Sztajzel, Ghislaine Wagner, Pierre R. Burkhard
Department of Neurology, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland
Joan Montaner
Neurovascular Research Laboratory, VHIR & Stroke Unit, Vall d'Hebron Hospital, Autonomous University of Barcelona (UAB), Catalonia, Spain

Corresponding Author

Email: natacha.turck@unige.ch

Competing Interests

Neither financial interest nor conflicts of interest are related to this work. Nevertheless, this Swiss study was funded by Proteome Sciences plc. UNIGE has granted to Proteome Sciences the exclusive (worldwide) license to a patent protecting GSTP and NDKA as brain damage markers. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: NT XR AH PRB JCS. Performed the experiments: NW CF GW. Analyzed the data: NT XR AH PRB RS JCS JM. Contributed reagents/materials/analysis tools: DFH RS PRB JCS JM. Wrote the paper: NT XR PRB RS JM DFH JCS.