About the Authors

Olga Horakova

Contributed equally to this work with: Olga Horakova, Dasa Medrikova

Affiliation Department of Adipose Tissue Biology, Institute of Physiology Academy of Sciences of the Czech Republic v.v.i., Prague, Czech Republic

Dasa Medrikova

Contributed equally to this work with: Olga Horakova, Dasa Medrikova

Affiliation Department of Adipose Tissue Biology, Institute of Physiology Academy of Sciences of the Czech Republic v.v.i., Prague, Czech Republic

Evert M. van Schothorst

Affiliation Department of Human and Animal Physiology, Wageningen University, Wageningen, The Netherlands

Annelies Bunschoten

Affiliation Department of Human and Animal Physiology, Wageningen University, Wageningen, The Netherlands

Pavel Flachs

Affiliation Department of Adipose Tissue Biology, Institute of Physiology Academy of Sciences of the Czech Republic v.v.i., Prague, Czech Republic

Vladimir Kus

Affiliation Department of Adipose Tissue Biology, Institute of Physiology Academy of Sciences of the Czech Republic v.v.i., Prague, Czech Republic

Ondrej Kuda

Affiliation Department of Adipose Tissue Biology, Institute of Physiology Academy of Sciences of the Czech Republic v.v.i., Prague, Czech Republic

Kristina Bardova

Affiliation Department of Adipose Tissue Biology, Institute of Physiology Academy of Sciences of the Czech Republic v.v.i., Prague, Czech Republic

Petra Janovska

Affiliation Department of Adipose Tissue Biology, Institute of Physiology Academy of Sciences of the Czech Republic v.v.i., Prague, Czech Republic

Michal Hensler

Affiliation Department of Adipose Tissue Biology, Institute of Physiology Academy of Sciences of the Czech Republic v.v.i., Prague, Czech Republic

Martin Rossmeisl

Affiliation Department of Adipose Tissue Biology, Institute of Physiology Academy of Sciences of the Czech Republic v.v.i., Prague, Czech Republic

Rui Wang-Sattler

Affiliation Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany

Cornelia Prehn

Affiliation Institute of Experimental Genetics, Genome Analysis Center, Helmholtz Zentrum München, Neuherberg, Germany

Jerzy Adamski

Affiliation Institute of Experimental Genetics, Genome Analysis Center, Helmholtz Zentrum München, Neuherberg, Germany

Thomas Illig

Current address: Hannover Unified Biobank, Hannover Medical School, Hannover, Germany

Affiliation Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, Neuherberg, Germany

Jaap Keijer

Affiliation Department of Human and Animal Physiology, Wageningen University, Wageningen, The Netherlands

Jan Kopecky

kopecky@biomed.cas.cz

Affiliation Department of Adipose Tissue Biology, Institute of Physiology Academy of Sciences of the Czech Republic v.v.i., Prague, Czech Republic

Competing Interests

The authors have read the journal’s policy and have the following conflict: The research leading to these results has been funded in part by EPAX AS (Norway). There are no patents, products in development, or marketed products to declare. This does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: J. Kopecky. Performed the experiments: OH DM EMS AB OK VK KB PJ MH CP JA. Analyzed the data: OK DM EMS PF J. Kopecky J. Keijer CP JA MR RW-S TI. Wrote the paper: OH DM PF OK MR EMS J. Keijer J. Kopecky.