About the Authors

Gyungah Jun

gyungah@bu.edu (GJ); farrer@bu.edu (LAF)

Affiliations Department of Medicine (Biomedical Genetics), Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Ophthalmology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Biostatistics, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America

Juliet A. Moncaster

Affiliation Department of Psychiatry, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America

Carolina Koutras

Affiliation Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada

Sudha Seshadri

Affiliations Department of Neurology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Framingham Heart Study, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America

Jacqueline Buros

Affiliation Department of Medicine (Biomedical Genetics), Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America

Ann C. McKee

Affiliations Department of Neurology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Pathology & Laboratory Medicine, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Boston University Alzheimer's Disease Center, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Geriatric Research Education Clinical Center, Bedford Veterans Administration Hospital, Bedford, Massachusetts, United States of America

Georges Levesque

Affiliation Neurosciences Research Centre-CHUL, Université Laval, Québec, Canada

Philip A. Wolf

Affiliations Department of Neurology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Epidemiology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Framingham Heart Study, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America

Peter St. George-Hyslop

Affiliations Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom

Lee E. Goldstein

Affiliations Department of Psychiatry, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Neurology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Pathology & Laboratory Medicine, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Boston University Alzheimer's Disease Center, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America

Lindsay A. Farrer

gyungah@bu.edu (GJ); farrer@bu.edu (LAF)

Affiliations Department of Medicine (Biomedical Genetics), Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Ophthalmology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Biostatistics, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Neurology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Department of Epidemiology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America, Boston University Alzheimer's Disease Center, Boston University Schools of Medicine and Public Health, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GJ LEG PStG-H LAF. Performed the experiments: JAM CK. Analyzed the data: GJ JB LAF. Contributed reagents/materials/analysis tools: SS ACM PAW. Wrote the paper: GJ PStG-H LEG LAF. Critically evaluated and edited the manuscript for intellectual content: GJ JAM SS GL PAW PStG-H LEG LAF. Provided study supervision: PStG-H LEG LAF.