About the Authors

Michael R. Marit

Affiliations Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada, Campbell Family Cancer Research Institute, Ontario Cancer Institute, Toronto, Ontario, Canada

Manprit Chohan

Affiliations Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada, Campbell Family Cancer Research Institute, Ontario Cancer Institute, Toronto, Ontario, Canada

Natasha Matthew

Affiliation Campbell Family Cancer Research Institute, Ontario Cancer Institute, Toronto, Ontario, Canada

Kai Huang

Affiliation Campbell Family Cancer Research Institute, Ontario Cancer Institute, Toronto, Ontario, Canada

Douglas A. Kuntz

Affiliation Campbell Family Cancer Research Institute, Ontario Cancer Institute, Toronto, Ontario, Canada

David R. Rose

Affiliations Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada, Campbell Family Cancer Research Institute, Ontario Cancer Institute, Toronto, Ontario, Canada, Department of Biology, University of Waterloo, Waterloo, Ontario, Canada

Dwayne L. Barber

dbarber@uhnres.utoronto.ca

Affiliations Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada, Campbell Family Cancer Research Institute, Ontario Cancer Institute, Toronto, Ontario, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MRM MC NM DLB. Performed the experiments: MRM MC NM KH. Analyzed the data: MRM MC NM DRR DLB. Contributed reagents/materials/analysis tools: MRM MC NM KH DAK DRR. Wrote the paper: MRM DLB. Generated the vector constructs: KH. Advised on structural modeling: DAK DRR.