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Research Article

Increased Microglia/Macrophage Gene Expression in a Subset of Adult and Pediatric Astrocytomas

  • Jane R. Engler,

    Affiliations: Department of Neurological Surgery, University of California San Francisco, San Francisco, California, United States of America, Brain Tumor Research Center, University of California San Francisco, San Francisco, California, United States of America

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  • Aaron E. Robinson,

    Affiliations: Department of Neurological Surgery, University of California San Francisco, San Francisco, California, United States of America, Brain Tumor Research Center, University of California San Francisco, San Francisco, California, United States of America

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  • Ivan Smirnov,

    Affiliation: Department of Neurological Surgery, University of California San Francisco, San Francisco, California, United States of America

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  • J. Graeme Hodgson,

    Affiliations: Department of Neurological Surgery, University of California San Francisco, San Francisco, California, United States of America, Division of Oncology, Pfizer, La Jolla, California, United states of America

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  • Mitchel S. Berger,

    Affiliations: Department of Neurological Surgery, University of California San Francisco, San Francisco, California, United States of America, Brain Tumor Research Center, University of California San Francisco, San Francisco, California, United States of America

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  • Nalin Gupta,

    Affiliations: Department of Neurological Surgery, University of California San Francisco, San Francisco, California, United States of America, Brain Tumor Research Center, University of California San Francisco, San Francisco, California, United States of America

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  • C. David James,

    Affiliations: Department of Neurological Surgery, University of California San Francisco, San Francisco, California, United States of America, Brain Tumor Research Center, University of California San Francisco, San Francisco, California, United States of America

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  • Annette Molinaro,

    Affiliations: Department of Neurological Surgery, University of California San Francisco, San Francisco, California, United States of America, Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, United States of America

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  • Joanna J. Phillips mail

    joanna.phillips@ucsf.edu

    Affiliations: Department of Neurological Surgery, University of California San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America, Brain Tumor Research Center, University of California San Francisco, San Francisco, California, United States of America

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  • Published: August 22, 2012
  • DOI: 10.1371/journal.pone.0043339

About the Authors

Jane R. Engler, Aaron E. Robinson, Ivan Smirnov, J. Graeme Hodgson, Mitchel S. Berger, Nalin Gupta, C. David James, Annette Molinaro, Joanna J. Phillips
Department of Neurological Surgery, University of California San Francisco, San Francisco, California, United States of America
Joanna J. Phillips
Department of Pathology, University of California San Francisco, San Francisco, California, United States of America
Annette Molinaro
Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, United States of America
Jane R. Engler, Aaron E. Robinson, Mitchel S. Berger, Nalin Gupta, C. David James, Joanna J. Phillips
Brain Tumor Research Center, University of California San Francisco, San Francisco, California, United States of America
J. Graeme Hodgson
Division of Oncology, Pfizer, La Jolla, California, United states of America

Corresponding Author

Email: joanna.phillips@ucsf.edu

Competing Interests

Co-author MSB is a PLoS ONE Editorial Board Member. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JRE AM JJP. Performed the experiments: JRE AR IS AM JJP. Analyzed the data: JRE AR IS AM JJP. Contributed reagents/materials/analysis tools: JGH MSB NG CDJ. Wrote the paper: JRE IS CDJ AM JJP.