About the Authors

Carlos Zgheib

Affiliation Departments of Pharmacology and Toxicology, School of Medicine, and Center for Excellence in Cardiovascular-Renal Research, The University of Mississippi Medical Center, Jackson, Mississippi, United States of America

Mazen Kurdi

Affiliation Department of Chemistry and Biochemistry, Faculty of Sciences, Lebanese University, Rafic Hariri Educational Campus, Hadath, Lebanon

Fouad A. Zouein

Affiliation Departments of Pharmacology and Toxicology, School of Medicine, and Center for Excellence in Cardiovascular-Renal Research, The University of Mississippi Medical Center, Jackson, Mississippi, United States of America

Barak W. Gunter

Affiliation Departments of Pharmacology and Toxicology, School of Medicine, and Center for Excellence in Cardiovascular-Renal Research, The University of Mississippi Medical Center, Jackson, Mississippi, United States of America

Brian A. Stanley

Affiliation Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

Joe Zgheib

Affiliation Department of Medicine, Division of Cardiology, Centre Hospitalier Universitaire de Nancy, Brabois, France

Damian G. Romero

Affiliation Department of Biochemistry, School of Medicine, and Center for Excellence in Cardiovascular-Renal Research, The University of Mississippi Medical Center, Jackson, Mississippi, United States of America

S. Bruce King

Affiliation Department of Chemistry, Wake Forest University, Winston-Salem, North Carolina, United States of America

Nazareno Paolocci

Affiliations Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Clinical Medicine Department, Section of General Pathology, University of Perugia, Perugia, Italy

George W. Booz

gbooz@umc.edu

Affiliation Departments of Pharmacology and Toxicology, School of Medicine, and Center for Excellence in Cardiovascular-Renal Research, The University of Mississippi Medical Center, Jackson, Mississippi, United States of America

Competing Interests

The authors have read the journal’s policy and have the following conflict: Nazareno Paolocci is a founder and stock holder of Cardioxyl Pharmaceuticals Inc. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: CZ FAZ MK GWB. Performed the experiments: CZ FAZ MK BWG BAS GWB. Analyzed the data: CZ FAZ MK BWG GWB. Contributed reagents/materials/analysis tools: JZ SBK NP DGR GWB. Wrote the paper: CZ MK FAZ JZ NP BAS GWB.