Drosophila Heat Shock Response Requires the JNK Pathway and Phosphorylation of Mixed Lineage Kinase at a Conserved Serine-Proline Motif

Rebecca L. Gonda; Rebecca A. Garlena; Beth Stronach

doi:10.1371/journal.pone.0042369

Loading metrics

Open Access

Peer-reviewed

Research Article

Drosophila Heat Shock Response Requires the JNK Pathway and Phosphorylation of Mixed Lineage Kinase at a Conserved Serine-Proline Motif

Rebecca L. Gonda,

Affiliation Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Rebecca A. Garlena,

Affiliation Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯
Beth Stronach

* E-mail: stronach@pitt.edu

Affiliation Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
⨯

Drosophila Heat Shock Response Requires the JNK Pathway and Phosphorylation of Mixed Lineage Kinase at a Conserved Serine-Proline Motif

Rebecca L. Gonda,
Rebecca A. Garlena,
Beth Stronach

Published: July 27, 2012
https://doi.org/10.1371/journal.pone.0042369

About the Authors

Rebecca L. Gonda

Affiliation Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

Rebecca A. Garlena

Affiliation Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

Beth Stronach

* E-mail: stronach@pitt.edu

Affiliation Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RLG RAG BS. Performed the experiments: RLG RAG BS. Analyzed the data: RLG RAG BS. Wrote the paper: RLG BS.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Phosphorylation
Is the Subject Area "Phosphorylation" applicable to this article?

Thanks for your feedback.
c-Jun N-terminal kinase signaling cascade
Is the Subject Area "c-Jun N-terminal kinase signaling cascade" applicable to this article?

Thanks for your feedback.
Stress signaling cascade
Is the Subject Area "Stress signaling cascade" applicable to this article?

Thanks for your feedback.
Heat shock response
Is the Subject Area "Heat shock response" applicable to this article?

Thanks for your feedback.
Drosophila melanogaster
Is the Subject Area "Drosophila melanogaster" applicable to this article?

Thanks for your feedback.
MAPK signaling cascades
Is the Subject Area "MAPK signaling cascades" applicable to this article?

Thanks for your feedback.
Thermal stresses
Is the Subject Area "Thermal stresses" applicable to this article?

Thanks for your feedback.
Cellular stress responses
Is the Subject Area "Cellular stress responses" applicable to this article?

Thanks for your feedback.