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Research Article

Rates of Decline in Alzheimer Disease Decrease with Age

  • Dominic Holland mail,

    dominic.holland@gmail.com

    Affiliation: Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America

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  • Rahul S. Desikan,

    Affiliation: Department of Radiology, University of California San Diego, La Jolla, California, United States of America

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  • Anders M. Dale,

    Affiliations: Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America, Department of Radiology, University of California San Diego, La Jolla, California, United States of America

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  • Linda K. McEvoy,

    Affiliation: Department of Radiology, University of California San Diego, La Jolla, California, United States of America

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  • for the Alzheimer’s Disease Neuroimaging Initiative
  • Published: August 02, 2012
  • DOI: 10.1371/journal.pone.0042325
  • Featured in PLOS Collections

About the Authors

Dominic Holland, Anders M. Dale
Department of Neurosciences, University of California San Diego, La Jolla, California, United States of America
Rahul S. Desikan, Anders M. Dale, Linda K. McEvoy
Department of Radiology, University of California San Diego, La Jolla, California, United States of America

Corresponding Author

Email: dominic.holland@gmail.com

Competing Interests

Anders M. Dale is a founder and holds equity in CorTechs Labs, Inc. and also serves on its Scientific Advisory Board. The terms of this arrangement have been reviewed and approved by the University of California, San Diego in accordance with its conflict of interest policies. Linda K. McEvoy’s spouse is President of CorTechs Labs, Inc. A patent application for Quarc has been filed through the UCSD Technology Transfer Office.

Author Contributions

Conceived and designed the experiments: DH. Performed the experiments: DH. Analyzed the data: DH. Contributed reagents/materials/analysis tools: DH AMD. Wrote the paper: DH RSD LKM. Responsible for the study concept and design, all levels of data analysis, drafting the report, tables, and figures: DH. Contributed critically to data interpretation and revision of the report: DH RSD LKM. Contributed to data acquisition and analysis: AMD.