About the Authors

Kimberly E. Hanson

kim.hanson@hsc.utah.edu (KEH); alexa011@mc.duke.edu (BDA)

Affiliation Departments of Medicine and Pathology, University of Utah, Salt Lake City, Utah, United States of America

Christopher D. Pfeiffer

Affiliation Department of Medicine, Oregon Health Sciences University, Portland, Oregon, United States of America

Erika D. Lease

Affiliation Department of Medicine, Duke University, Durham, North Carolina, United States of America

Alfred H. Balch

Affiliation Department of Pediatrics, University of Utah, Salt Lake City, Utah, United States of America

Aimee K. Zaas

Affiliation Department of Medicine, Duke University, Durham, North Carolina, United States of America

John R. Perfect

Affiliation Department of Medicine, Duke University, Durham, North Carolina, United States of America

Barbara D. Alexander

kim.hanson@hsc.utah.edu (KEH); alexa011@mc.duke.edu (BDA)

Affiliation Department of Medicine, Duke University, Durham, North Carolina, United States of America

Competing Interests

This study was supported by an investigator-initiated grant from Pfizer, Inc. There are no other relevant declarations relating to this study and employment, consultancy, patents, or products to disclose. The funding source did not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: KEH JRP BDA. Analyzed the data: KEH JRP BDA. Wrote the paper: KEH JRP BDA. Clinical Data Collection: AKZ CDP EDL. Critical Manuscript review: AKZ CDP EDL AHB. Statistical analysis: AHB.