About the Authors

Christopher Fuller

Affiliation Royal Free Campus, University College London Medical School, University College, London, United Kingdom

Susan Michie

Affiliation University College London, London, United Kingdom

Joanne Savage

Affiliation Royal Free Campus, University College London Medical School, University College, London, United Kingdom

John McAteer

Affiliation University College London, London, United Kingdom

Sarah Besser

Current address: King's College London, London, England

Affiliation Royal Free Campus, University College London Medical School, University College, London, United Kingdom

Andre Charlett

Affiliation Health Protection Agency, London, United Kingdom

Andrew Hayward

Affiliation Royal Free Campus, University College London Medical School, University College, London, United Kingdom

Barry D. Cookson

Affiliation Health Protection Agency, London, United Kingdom

Ben S. Cooper

Current address: Mahidol University Tropical Medicine Research Unit, Bangkok, Thailand

Affiliation Health Protection Agency, London, United Kingdom

Georgia Duckworth

Affiliation Health Protection Agency, London, United Kingdom

Annette Jeanes

Affiliation University College London Hospitals, London, United Kingdom

Jenny Roberts

Affiliation London School of Hygiene and Tropical Medicine, London, United Kingdom

Louise Teare

Affiliation Mid-Essex NHS Trust, Chelmsford, United Kingdom

Sheldon Stone

s.stone@medsch.ucl.ac.uk

Affiliation Royal Free Campus, University College London Medical School, University College, London, United Kingdom

Competing Interests

Barry Cookson has received consultancy fees from Wyeth (vaccines), Carefusion (chlorhexidine preparations), Baxter (intravenous lines), 3M, Rubbermaid, and Spire (infection control) and lecture fees from Wyeth. Sheldon Stone received grant funding from GOJO industries. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SM JM SPS AH BDC AC BSC JR GD AJ LT. Performed the experiments: CF JS SB JM. Analyzed the data: AC CF JS. Wrote the paper: CF SPS SM AH BDC BSC AC. Formed the final writing committee: CF SPS SM AH BDC BSC AC. Wrote first draft written: CF. Wrote subsequent drafts: SPS. Approved the final manuscript: CF SM JS JM SB AC AH BDC BSC GD AJ JR LT SS. Made additional revisions to refine the intellectual content of earlier versions of the paper: CF SM JS JM SB AC AH BDC BSC GD AJ JR LT SS.