About the Authors

Vaibhav Saini

Current address: Endocrine Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Affiliation Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Curtis D. Hose

Affiliation SAIC-Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Anne Monks

Affiliation SAIC-Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Kunio Nagashima

Affiliation SAIC-Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Bingnan Han

Affiliation SAIC-Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Dianne L. Newton

Affiliation SAIC-Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Angelena Millione

Affiliation SAIC-Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Jalpa Shah

Affiliation SAIC-Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Melinda G. Hollingshead

Affiliation Biological Testing Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Karen M. Hite

Affiliation SAIC-Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Mark W. Burkett

Affiliation SAIC-Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Rene M. Delosh

Affiliation SAIC-Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Thomas E. Silvers

Affiliation SAIC-Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Dominic A. Scudiero

Affiliation SAIC-Frederick, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Robert H. Shoemaker

Shoemakr@mail.nih.gov

Affiliation Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist. There are no financial, personal, or professional interests that could be construed to have influenced the paper. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: VS RHS. Performed the experiments: VS CDH A. Monks KN BH DLN A. Millione JS MGH KMH MWB RMD TES. Analyzed the data: VS CDH A. Monks KN BH DLN DAS RHS. Contributed reagents/materials/analysis tools: RHS. Wrote the paper: VS RHS. Revising manuscript content: VS KN BH DLN RHS. Approving final version of manuscript: RHS.