About the Authors

Anthony A. Fodor

Affiliation Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, Charlotte, North Carolina, United States of America

Todd Z. DeSantis

Affiliation Bioinformatics Department, Second Genome, Inc., San Bruno, California, United States of America

Kristine M. Wylie

Affiliation Department of Genetics, The Genome Institute, Washington University School of Medicine, St. Louis, Missouri, United States of America

Jonathan H. Badger

Affiliation Microbial and Environmental Genomics Department. J. Craig Venter Institute, San Diego, California, United States of America

Yuzhen Ye

Affiliation School of Informatics and Computing, Indiana University, Bloomington, Indiana, United States of America

Theresa Hepburn

Affiliation Genome Sequencing and Analysis Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Ping Hu

Affiliation Earth Science Division, Ecology Department, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America

Erica Sodergren

Affiliation Department of Genetics, The Genome Institute, Washington University School of Medicine, St. Louis, Missouri, United States of America

Konstantinos Liolios

Affiliation Microbial Genomics and Metagenomics Program, Department of Energy Joint Genome Institute, Walnut Creek, California, United States of America

Heather Huot-Creasy

Affiliation Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Bruce W. Birren

Affiliation Genome Sequencing and Analysis Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Ashlee M. Earl

aearl@broadinstitute.org

Affiliation Genome Sequencing and Analysis Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Competing Interests

One author is affiliated with the company Second Genome. His employment at this company does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials. Furthermore, the other authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AF TD KW ES JB BB AE. Performed the experiments: AF TD KW JB TH AE. Analyzed the data: AF AE. Contributed reagents/materials/analysis tools: AF TD PH YY KL HH-C. Wrote the paper: AF AE.