About the Authors

Xiomara V. Thomas

Contributed equally to this work with: Xiomara V. Thomas, Joep de Bruijne

x.v.thomas@amc.uva.nl

Affiliation Academic Medical Center, Department of Medical Microbiology, Section of Clinical Virology, Amsterdam, The Netherlands

Joep de Bruijne

Contributed equally to this work with: Xiomara V. Thomas, Joep de Bruijne

Affiliation Academic Medical Center, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands

James C. Sullivan

Affiliation Vertex Pharmaceuticals Incorporated, Cambridge, Massachusetts, United States of America

Tara L. Kieffer

Affiliation Vertex Pharmaceuticals Incorporated, Cambridge, Massachusetts, United States of America

Cynthia K. Y. Ho

Affiliation Academic Medical Center, Department of Medical Microbiology, Section of Clinical Virology, Amsterdam, The Netherlands

Sjoerd P. Rebers

Affiliation Academic Medical Center, Department of Medical Microbiology, Section of Clinical Virology, Amsterdam, The Netherlands

Michel de Vries

Affiliation Academic Medical Center, Department of Medical Microbiology, Section of Human Retro Virology, Amsterdam, The Netherlands

Hendrik W. Reesink

Affiliation Academic Medical Center, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands

Christine J. Weegink

Affiliation Academic Medical Center, Department of Gastroenterology and Hepatology, Amsterdam, The Netherlands

Richard Molenkamp

Affiliation Academic Medical Center, Department of Medical Microbiology, Section of Clinical Virology, Amsterdam, The Netherlands

Janke Schinkel

Affiliation Academic Medical Center, Department of Medical Microbiology, Section of Clinical Virology, Amsterdam, The Netherlands

Competing Interests

The authors have read the journal's policy and have the following conflicts: HR serves as advisor for Roche Molecular Diagnostics, Anadys, Merck, Arrows, and Gilead, consults for PRA-International, Tibotec, GlaxoSmithKline, Chiron Novartis, and Roche Therapeutics, and receives grant/research support from Merck & Co. TK and J. Sullivan are employees and stock owners of Vertex Pharmaceuticals Incorporated. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. All other authors have nothing to disclose.

Author Contributions

Conceived and designed the experiments: XVT JdB J. Schinkel RM HR. Performed the experiments: XVT SPR. Analyzed the data: XVT RM J. Schinkel CKYH TK J. Sullivan. Contributed reagents/materials/analysis tools: MdV RM TK J. Sullivan. Wrote the paper: XVT JdB J. Schinkel. Helped with study set-up: CJW.