Pulmonary Infection with Influenza A Virus Induces Site-Specific Germinal Center and T Follicular Helper Cell Responses

Alexander W. Boyden; Kevin L. Legge; Thomas J. Waldschmidt

doi:10.1371/journal.pone.0040733

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Peer-reviewed

Research Article

Pulmonary Infection with Influenza A Virus Induces Site-Specific Germinal Center and T Follicular Helper Cell Responses

Alexander W. Boyden,

Affiliations Interdisciplinary Graduate Program in Immunology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, United States of America, Department of Pathology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, United States of America
⨯
Kevin L. Legge,

Affiliations Interdisciplinary Graduate Program in Immunology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, United States of America, Department of Pathology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, United States of America, Department of Microbiology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, United States of America
⨯
Thomas J. Waldschmidt

* E-mail: thomas-waldschmidt@uiowa.edu

Affiliations Interdisciplinary Graduate Program in Immunology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, United States of America, Department of Pathology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, United States of America
⨯

Pulmonary Infection with Influenza A Virus Induces Site-Specific Germinal Center and T Follicular Helper Cell Responses

Alexander W. Boyden,
Kevin L. Legge,
Thomas J. Waldschmidt

Published: July 11, 2012
https://doi.org/10.1371/journal.pone.0040733

About the Authors

Alexander W. Boyden

Kevin L. Legge

Affiliations Interdisciplinary Graduate Program in Immunology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, United States of America, Department of Pathology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, United States of America, Department of Microbiology, Carver College of Medicine, The University of Iowa, Iowa City, Iowa, United States of America

Thomas J. Waldschmidt

* E-mail: thomas-waldschmidt@uiowa.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AWB TJW. Performed the experiments: AWB. Analyzed the data: AWB KLL TJW. Contributed reagents/materials/analysis tools: AWB KLL TJW. Wrote the paper: AWB TJW.

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B cells
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Spleen
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Influenza A virus
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Respiratory infections
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Cytokines
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Lungs
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T cells
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