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Research Article

Incidence, Clinical Spectrum, Risk Factors and Impact of HIV-Associated Immune Reconstitution Inflammatory Syndrome in South Africa

  • Lewis John Haddow,

    Affiliations: Centre for Sexual Health and HIV Research, Research Department of Infection and Population Health, University College London, London, United Kingdom, Department of Infectious Diseases, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa

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  • Mahomed-Yunus Suleman Moosa,

    Affiliation: Department of Infectious Diseases, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa

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  • Anisa Mosam,

    Affiliation: Department of Dermatology, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa

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  • Pravi Moodley,

    Affiliations: Department of Virology, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa, National Health Laboratory Services, Inkosi Albert Luthuli Central Hospital, Durban, South Africa

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  • Raveen Parboosing,

    Affiliations: Department of Virology, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa, National Health Laboratory Services, Inkosi Albert Luthuli Central Hospital, Durban, South Africa

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  • Philippa Jane Easterbrook mail

    easterbrookp@who.int

    Affiliation: Department of Infectious Diseases, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa

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  • Published: November 12, 2012
  • DOI: 10.1371/journal.pone.0040623

About the Authors

Lewis John Haddow
Centre for Sexual Health and HIV Research, Research Department of Infection and Population Health, University College London, London, United Kingdom
Lewis John Haddow, Mahomed-Yunus Suleman Moosa, Philippa Jane Easterbrook
Department of Infectious Diseases, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa
Anisa Mosam
Department of Dermatology, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa
Pravi Moodley, Raveen Parboosing
Department of Virology, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa
Pravi Moodley, Raveen Parboosing
National Health Laboratory Services, Inkosi Albert Luthuli Central Hospital, Durban, South Africa

Corresponding Author

Email: easterbrookp@who.int

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LH MYSM PM RP PE. Performed the experiments: LH MYSM AM PM RP PE. Analyzed the data: LH PE. Wrote the paper: LH PE.