About the Authors

Shi-He Liu

Affiliations Department of Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, United States of America

Donald D. Rao

Affiliation Gradalis, Inc., Dallas, Texas, United States of America

John Nemunaitis

Affiliations Gradalis, Inc., Dallas, Texas, United States of America, Mary Crowley Cancer Research Centers, Dallas, Texas, United States of America, Texas Oncology, P.A., Dallas, Texas, United States of America

Neil Senzer

Affiliations Gradalis, Inc., Dallas, Texas, United States of America, Mary Crowley Cancer Research Centers, Dallas, Texas, United States of America, Texas Oncology, P.A., Dallas, Texas, United States of America

Guisheng Zhou

Affiliations Department of Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, United States of America

David Dawson

Affiliation Department of Pathology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America

Marie-Claude Gingras

Affiliation Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America

Zhaohui Wang

Affiliation Gradalis, Inc., Dallas, Texas, United States of America

Richard Gibbs

Affiliation Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America

Michael Norman

Affiliation Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, United States of America

Nancy S. Templeton

Affiliation Gradalis, Inc., Dallas, Texas, United States of America

Francesco J. DeMayo

Affiliation Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America

Bert O'Malley

Affiliation Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America

Robbi Sanchez

Affiliation Department of Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America

William E. Fisher

Affiliations Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, United States of America, Elkins Pancreas Center, Baylor College of Medicine, Houston, Texas, United States of America

F. Charles Brunicardi

cbrunicardi@mednet.ucla.edu

Affiliations Department of Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, United States of America, Elkins Pancreas Center, Baylor College of Medicine, Houston, Texas, United States of America

Competing Interests

D. Rao, N. Senzer, Z. Wang and N. Templeton are employed by Gradalis, Inc. The following authors are shareholders in Gradalis, Inc.: N. Senzer, F.C. Brunicardi, D. Rao and J. Nemunaitis. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: FCB. Performed the experiments: S-HL GZ ZW MN RS. Analyzed the data: S-HL JN M-CG ZW FCB. Contributed reagents/materials/analysis tools: MN DR JN DD NT FD WF. Wrote the paper: FCB S-HL DR JM NS RG FD BO WF.