About the Authors

John D. Kelly

Contributed equally to this work with: John D. Kelly, Tim J. Dudderidge

Affiliation Department of Pathology and Cancer Institute, University College London, London, United Kingdom

Tim J. Dudderidge

Contributed equally to this work with: John D. Kelly, Tim J. Dudderidge

Affiliations Department of Pathology and Cancer Institute, University College London, London, United Kingdom, The Royal Marsden National Health Service (NHS) Foundation Trust, London, United Kingdom

Alex Wollenschlaeger

gareth.williams@ucl.ac.uk (AW)

Affiliation Wolfson Institute for Biomedical Research, University College London, London, United Kingdom

Odu Okoturo

Affiliation Department of Medicine, Imperial College London, London, United Kingdom

Keith Burling

Affiliation Department of Clinical Biochemistry, Addenbrooke’s Hospital, University of Cambridge, Cambridge, United Kingdom

Fiona Tulloch

Affiliation Department of Clinical Biochemistry, Addenbrooke’s Hospital, University of Cambridge, Cambridge, United Kingdom

Ian Halsall

Affiliation Department of Clinical Biochemistry, Addenbrooke’s Hospital, University of Cambridge, Cambridge, United Kingdom

Teresa Prevost

Affiliation Department of Public Health and Primary Care, Centre for Applied Medical Statistics, University of Cambridge, Institute of Public Health, Cambridge, United Kingdom

Andrew Toby Prevost

Affiliation Department of Primary Care and Public Health Sciences, King’s College London, London, United Kingdom

Joana C. Vasconcelos

Affiliation Department of Public Health and Primary Care, Centre for Applied Medical Statistics, University of Cambridge, Institute of Public Health, Cambridge, United Kingdom

Wendy Robson

Affiliation Department of Urology, Freeman Hospital, Newcastle upon Tyne, United Kingdom

Hing Y. Leung

Affiliation Beatson Institute for Cancer Research, University of Glasgow, Bearsden, Glasgow, United Kingdom

Nikhil Vasdev

Affiliation Department of Urology, Freeman Hospital, Newcastle upon Tyne, United Kingdom

Robert S. Pickard

Affiliation Department of Urology, Freeman Hospital, Newcastle upon Tyne, United Kingdom

Gareth H. Williams

gareth.williams@ucl.ac.uk (AW)

Affiliations Department of Pathology and Cancer Institute, University College London, London, United Kingdom, Wolfson Institute for Biomedical Research, University College London, London, United Kingdom

Kai Stoeber

Affiliations Department of Pathology and Cancer Institute, University College London, London, United Kingdom, Wolfson Institute for Biomedical Research, University College London, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JDK HYL TJD GHW KS. Performed the experiments: AW OO KB FT IH WR. Analyzed the data: JDK TJD HYL AW TP ATP JCV NV RSP GHW KS. Contributed reagents/materials/analysis tools: JCV ATP. Wrote the paper: JDK TJD AW ATP GHW KS.