A Synthetic Peptide with the Putative Iron Binding Motif of Amyloid Precursor Protein (APP) Does Not Catalytically Oxidize Iron

Kourosh Honarmand Ebrahimi; Peter-Leon Hagedoorn; Wilfred R. Hagen

doi:10.1371/journal.pone.0040287

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Open Access

Peer-reviewed

Research Article

A Synthetic Peptide with the Putative Iron Binding Motif of Amyloid Precursor Protein (APP) Does Not Catalytically Oxidize Iron

Kourosh Honarmand Ebrahimi,

Affiliation Department of Biotechnology, Delft University of Technology, Delft, The Netherlands
⨯
Peter-Leon Hagedoorn,

Affiliation Department of Biotechnology, Delft University of Technology, Delft, The Netherlands
⨯
Wilfred R. Hagen

* E-mail: w.r.hagen@tudelft.nl

Affiliation Department of Biotechnology, Delft University of Technology, Delft, The Netherlands
⨯

A Synthetic Peptide with the Putative Iron Binding Motif of Amyloid Precursor Protein (APP) Does Not Catalytically Oxidize Iron

Kourosh Honarmand Ebrahimi,
Peter-Leon Hagedoorn,
Wilfred R. Hagen

Published: August 14, 2012
https://doi.org/10.1371/journal.pone.0040287

About the Authors

Kourosh Honarmand Ebrahimi

Affiliation Department of Biotechnology, Delft University of Technology, Delft, The Netherlands

Peter-Leon Hagedoorn

Affiliation Department of Biotechnology, Delft University of Technology, Delft, The Netherlands

Wilfred R. Hagen

* E-mail: w.r.hagen@tudelft.nl

Affiliation Department of Biotechnology, Delft University of Technology, Delft, The Netherlands

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KHE WRH. Performed the experiments: KHE. Analyzed the data: KHE PLH WRH. Contributed reagents/materials/analysis tools: KHE. Wrote the paper: KHE PLH WRH.

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Oxidation
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Ferritin
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Oxygen
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Isothermal titration calorimetry
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Bicinchoninic acid assay
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Synthetic peptides
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