About the Authors
- Thomas S. Peat
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* E-mail: tom.peat@csiro.au
Affiliation CSIRO Materials, Science and Engineering, Parkville, Victoria, Australia
- David I. Rhodes
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Current address: JDJ Bioservices Ltd, Melbourne, Victoria, Australia
Affiliation Avexa Ltd, Melbourne, Victoria, Australia
- Nick Vandegraaff
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Affiliation Avexa Ltd, Melbourne, Victoria, Australia
- Giang Le
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Affiliation Avexa Ltd, Melbourne, Victoria, Australia
- Jessica A. Smith
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Affiliation Avexa Ltd, Melbourne, Victoria, Australia
- Lisa J. Clark
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Affiliation Avexa Ltd, Melbourne, Victoria, Australia
- Eric D. Jones
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Affiliation Avexa Ltd, Melbourne, Victoria, Australia
- Jonathan A. V. Coates
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Affiliation Avexa Ltd, Melbourne, Victoria, Australia
- Neeranat Thienthong
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Affiliation Avexa Ltd, Melbourne, Victoria, Australia
- Janet Newman
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Affiliation CSIRO Materials, Science and Engineering, Parkville, Victoria, Australia
- Olan Dolezal
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Affiliation CSIRO Materials, Science and Engineering, Parkville, Victoria, Australia
- Roger Mulder
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Affiliation CSIRO Materials, Science and Engineering, Clayton, Victoria, Australia
- John H. Ryan
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Affiliation CSIRO Materials, Science and Engineering, Clayton, Victoria, Australia
- G. Paul Savage
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Affiliation CSIRO Materials, Science and Engineering, Clayton, Victoria, Australia
- Craig L. Francis
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Affiliation CSIRO Materials, Science and Engineering, Clayton, Victoria, Australia
- John J. Deadman
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Current address: Chemocopeia Ltd, Carlton, Melbourne, Victoria, Australia
Affiliation Avexa Ltd, Melbourne, Victoria, Australia
Competing Interests
Parts of this study were completed while David I. Rhodes, Nick Vandegraaff, Giang Le, Jessica A. Smith, Lisa J. Clark, Eric D. Jones, Jonathan A.V. Coates, Neeranat Thienthon and John J. Deadman were employed by Avexa Ltd. The work was supported by a commercial ready grant COMO4229 from the Commonwealth of Australia, Department of Innovation, Industry, Science and Research to Avexa. In this study, Compounds 4–11 were designed at Avexa Ltd using the Accelrys Discovery suite. There are no further patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.
Author Contributions
Conceived and designed the experiments: TSP JJD DIR. Performed the experiments: TSP DIR NV GL JAS LJC EDJ NT JN OD RM JHR CLF JJD. Analyzed the data: TSP DIR JN JAVC OD RM JHR GPS JJD. Contributed reagents/materials/analysis tools: TSP DIR OD JN RM JJD. Wrote the paper: TSP OD JJD.