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Research Article

Antibacterial Activity and Mechanism of a Scorpion Venom Peptide Derivative In Vitro and In Vivo

  • Luyang Cao equal contributor,

    equal contributor Contributed equally to this work with: Luyang Cao, Chao Dai

    Affiliation: State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, P. R. China

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  • Chao Dai equal contributor,

    equal contributor Contributed equally to this work with: Luyang Cao, Chao Dai

    Affiliation: State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, P. R. China

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  • Zhongjie Li,

    Affiliation: State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, P. R. China

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  • Zheng Fan,

    Affiliation: State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, P. R. China

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  • Yu Song,

    Affiliation: State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, P. R. China

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  • Yingliang Wu,

    Affiliation: State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, P. R. China

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  • Zhijian Cao mail,

    zjcao@whu.edu.cn (ZC); liwxlab@whu.edu.cn (WL)

    Affiliation: State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, P. R. China

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  • Wenxin Li mail

    zjcao@whu.edu.cn (ZC); liwxlab@whu.edu.cn (WL)

    Affiliation: State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, P. R. China

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  • Published: July 05, 2012
  • DOI: 10.1371/journal.pone.0040135

About the Authors

Luyang Cao, Chao Dai, Zhongjie Li, Zheng Fan, Yu Song, Yingliang Wu, Zhijian Cao, Wenxin Li
State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, P. R. China

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LC ZC CD. Performed the experiments: LC CD ZL ZF YS. Analyzed the data: LC ZC YW WL. Contributed reagents/materials/analysis tools: LC ZC YW WL. Wrote the paper: LC ZC.