About the Authors

George Tzertzinis

Affiliation New England Biolabs, Inc., Ipswich, Massachusetts, United States of America

Ezra Schildkraut

Affiliation CerroSci LLC, Ipswich, Massachusetts, United States of America

Ira Schildkraut

schildkraut@neb.com

Affiliation CerroSci LLC, Ipswich, Massachusetts, United States of America

Competing Interests

George Tzertzinis was employed by New England Biolabs, Inc. and Ezra Schildkraut and Ira Schildkraut by CerroSci LLC while performing this research. New England Biolabs and CerroSci funded this work. Coelenterazine, cypridina luciferin and Biolux GLuc Flex Assay Buffer were obtained from New England Biolabs. There are no further patents, products in development or marketed products to declare. This does not alter the authors‘ adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: GT IS ES. Performed the experiments: GT IS ES. Analyzed the data: GT IS ES. Contributed reagents/materials/analysis tools: GT IS ES. Wrote the paper: GT IS ES.