About the Authors

Xiaoxia Jin

Affiliations Department of Biomedical Engineering, Cleveland Clinic, Cleveland, Ohio, United States of America, William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, United States of America

Stewart Abbot

Affiliation Celgene Cellular Therapeutics, Warren, New Jersey, United States of America

Xiaokui Zhang

Affiliation Celgene Cellular Therapeutics, Warren, New Jersey, United States of America

Lin Kang

Affiliation Celgene Cellular Therapeutics, Warren, New Jersey, United States of America

Vanessa Voskinarian-Berse

Affiliation Celgene Cellular Therapeutics, Warren, New Jersey, United States of America

Rui Zhao

Affiliation McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

Marina V. Kameneva

Affiliation McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

Lee R. Moore

Affiliation Department of Biomedical Engineering, Cleveland Clinic, Cleveland, Ohio, United States of America

Jeffrey J. Chalmers

Affiliation William G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio, United States of America

Maciej Zborowski

zborowm@ccf.org

Affiliation Department of Biomedical Engineering, Cleveland Clinic, Cleveland, Ohio, United States of America

Competing Interests

JJC, LRM and MZ are co-authors of patents assigned to Cleveland Clinic and The Ohio State University, issued, licensed and pending that are related to certain aspects of equipment and methods developed for the purpose of this study. SA, XZ, LK and VV-B are employees of Celgene Cellular Therapeutics, Inc. (CCT) who collaborate and share materials with the rest of co-authors as supported by Defence Advanced Research Projects Agency (DARPA) funding (see Financial Disclosure). This does not alter the authors' adherence to all PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: XZ MVK JJC MZ. Performed the experiments: XJ LK VVB RZ LRM. Analyzed the data: XJ XZ RZ MVK LRM JJC MZ. Contributed reagents/materials/analysis tools: SA MVK JJC MZ. Wrote the paper: XJ SA XZ MVK LRM JJC MZ.